New drug cocktail aims to ease Post-Spine surgery pain
NCT ID NCT07523321
First seen Apr 14, 2026 · Last updated Jun 23, 2026 · Updated 9 times
Summary
This study tests whether giving a combination of two drugs, dexmedetomidine and esketamine, during and after spinal surgery can lower the chance of moderate-to-severe pain. About 274 adults aged 40 to 79 having spine surgery will take part. The goal is to see if this combo works better than standard pain relief.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for POSTOPERATIVE ANALGESIA are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Email: •••••@•••••
Locations
-
Peking University First Hospital
Beijing, Beijing Municipality, 100034, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexmedetomidine and esketamine
What this could lead to
If this works, it could offer a better way to manage pain after spinal surgery, reducing the need for strong opioids and improving recovery.
What could go wrong
This is a Phase 4 trial, but it's still early to know if the combination is truly better than standard care. The results may not apply to all types of surgery or patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.