New study aims to cut opioid use after back surgery with targeted nerve blocks
NCT ID NCT06851533
First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 2 times
Summary
This study compares two types of nerve blocks (TLIP and Quadro Iliac) to see which one better reduces pain and the need for strong painkillers after lumbar microdiscectomy surgery for herniated discs. About 90 adults having this back surgery will receive one of the two blocks before surgery. The main goal is to measure how much pain medication they need in the first 24 hours after surgery, and also track pain scores and side effects.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18 to 80 years * American Society of Anesthesiologists (ASA) physical status I to III * scheduled for lumbar microdiscectomy surgery Exclusion Criteria: * Known allergy to local anesthetics * Any other significant drug allergies related to the study interventions * Pregnancy * Pre-existing psychiatric or neurological disorders * Inability to provide informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Medipol University
RECRUITINGIstanbul, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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- Could opioid tolerance dull the power of local anesthetics?