New pain block tested against standard for abdominal surgery recovery

NCT ID NCT06409156

Symptom relief Sponsor: The Cleveland Clinic Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two types of nerve blocks for pain after open upper abdominal surgery. One is a newer technique (EOIFP block) and the other is a standard one (OSTAP block). The goal is to see how easy it is for doctors to learn the new block. 100 adults having surgery at Cleveland Clinic will take part.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: nerve block (local anesthetic injection)
What this could lead to: If one block works better, it could improve pain control and reduce opioid use after abdominal surgery.
What could go wrong: This is a small, early pilot study focused on feasibility, not on proving which block is better. Results may not apply to all surgeries or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2024

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Written informed consent; * 18-85 years old; * ASA Physical Status 1-3 * Scheduled for elective open upper abdominal surgery with supraumbilical incision (gastrectomy, hepatectomy, pancreatectomy, splenectomy, supraumbilical ventral hernia repair). * Anticipated hospitalization of three nights; * Expected requirement for parenteral opioids for at least 48 hours for postoperative pain Exclusion Criteria: * Hepatic disease, e.g. twice the normal levels of liver enzymes; * Chronic kidney disease according to GFR (may be stage 3 or worse as defined by a GFR \<60 * Allergic reaction to study medications; * Women who are pregnant or breastfeeding; * Nephrectomy or lower abdominal surgeries such as hysterectomy, colorectal surgeries * Patient refusal

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Open abdominal surgery

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

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New pain block tested against standard for abdominal surgery recovery

What the study statuses mean