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Hands-On therapy vs. exercise: which eases jaw pain better?

NCT ID NCT07534540

Symptom relief Sponsor: Alanya Alaaddin Keykubat University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two non-drug approaches for temporomandibular disorder (TMD), a condition causing jaw pain and stiffness. Fifty adults with TMD were randomly assigned to receive either osteopathic manipulative treatment (hands-on therapy) or a home exercise program. Researchers measured pain, jaw movement, posture, and quality of life before and after treatment to see which approach worked better.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Apr 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: TMD Group: * Diagnosis of temporomandibular disorder (TMD) confirmed by a dentist * Pain intensity ≥ 3.5 cm on the Visual Analog Scale (VAS) * Presence of TMD-related pain for at least 3 months * Aged between 18 and 50 years * Willingness to participate in the study Control Group: * No history or clinical signs of temporomandibular disorder (TMD) * Aged between 18 and 50 years * Willingness to participate in the study Exclusion Criteria: TMD Group: * Presence of any condition other than TMD that may affect the assessment outcomes * Presence of musculoskeletal pain in any other body region * Any orthopedic or neurological condition that may interfere with assessments * Diagnosed psychiatric disorder * Conditions impairing communication or ability to complete assessments * Illiteracy * History of orthopedic surgery in any body region * Presence of systemic pathological conditions such as fractures, rheumatoid arthritis, or suspected malingering * Receipt of physiotherapy or other treatment targeting the temporomandibular joint or spinal region within the last 6 months Control Group: * History of chronic musculoskeletal disorders within the past year * Any orthopedic or neurological condition that may interfere with assessments * Diagnosed psychiatric disorder * Conditions impairing communication or ability to complete assessments * Illiteracy

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Conditions

The condition(s) this trial relates to.

myofascial pain syndrome temporomandibular joint disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteoapthic manipulation treatment Temporomandibular disorder (TMD)

Contacts and locations

Locations

  • Alanya Alaaddin Keykubat University

    Antalya, Alanya, 07400, Turkey (Türkiye)

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