Nighttime breathing trouble linked to hidden heart damage
NCT ID NCT07315399
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how low oxygen levels during sleep (from obstructive sleep apnea) are connected to problems in the tiny blood vessels of the heart. Researchers will follow 560 adults with suspected heart issues to see if sleep apnea patterns can predict future heart events like heart attacks. The goal is to find better ways to identify heart risks early.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 560 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Suspected myocardial ischemia patients underwent PSG to acquire detailed parameters of OSA-related nocturnal hypoxemia.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Aged 18 to 80 years, of any gender. 2. Scheduled for elective coronary angiography due to symptoms or evidence of myocardial ischemia. 3. Agreed to and capable of completing overnight polysomnography (PSG) monitoring. 4. Provided written informed consent and were willing and able to comply with baseline assessments and long-term follow-up. Exclusion Criteria: 1. Presence of coronary chronic total occlusion (CTO), history of coronary artery bypass grafting (CABG), severe valvular heart disease, dilated or hypertrophic cardiomyopathy, congenital heart disease, or heart failure (NYHA functional class III-IV). 2. Sleep-disordered breathing with central sleep apnea (CSA) as the primary manifestation. 3. Severe hepatic insufficiency (Child-Pugh class C) or renal failure (eGFR \< 30 mL/min/1.73 m²). 4. Pregnancy or lactation. 5. Life expectancy of less than 2 years, or any other condition that the investigators considered unsuitable for participation in the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Beijing Anzhen Hospital, Capital Medical University
Beijing, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could High-Intensity workouts and diet tame chest pain from tiny heart vessels?
- Can an Hourglass-Shaped device relieve chest pain when arteries Aren't blocked?
- Can a pill replace the CPAP machine for sleep apnea?
- Microplastics in your blood: a hidden heart risk?