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Microplastics in your blood: a hidden heart risk?

NCT ID NCT07748767

Knowledge-focused Sponsor: Beijing Anzhen Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 06, 2026 · Last updated Aug 21, 2026 · Updated 2 times

Summary

This study looks at whether tiny plastic particles in the blood are linked to problems with the heart's small blood vessels. Researchers will measure microplastic levels in 184 people who are already having a heart procedure, and then check their heart vessel function and track their health for two years. The goal is to see if higher plastic exposure is associated with worse heart outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
micro-nanoplastic examination (blood test for microplastics)
What this could lead to
If microplastics are found to harm heart blood vessels, this could lead to new ways to prevent or treat heart disease by reducing plastic exposure.
What could go wrong
This is an observational study, so it can only show a link, not prove cause and effect. The results may be affected by other factors, and the study is relatively small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 184 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2027

An estimate. Start dates often move.

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients older than 18 years old, with clinical indications for planned invasive coronary angiography and coronary functional assessment.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18; * Patients with clinical indications for undergoing invasive coronary angiography and coronary functional assessment (including fractional flow reserve \[FFR\], CFR, and IMR); * Voluntarily sign the written informed consent form. Exclusion Criteria: * The surgeon (or attending physician) determines that the patient is not suitable for or cannot tolerate a coronary physiological examination; * Intraoperative coronary angiography reveals a stenosis of\>90% in any non-left main coronary artery lumen or a stenosis of\>50% in the left main coronary artery lumen; * Left ventricular ejection fraction \<35% or cardiogenic shock or cardiac arrest; * Previous history of invasive procedures/treatments; * Active inflammatory diseases; * Connective tissue disease; * History of malignant tumors; * Expected lifespan \<2 years; * Pregnancy or lactation; * Subjects who refuse to comply with the pollution control measures set in this study; * Currently participating in other interventional clinical trials.

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Conditions

The condition(s) this trial relates to.

coronary microvascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronary microvascular dysfunction (CMD) MACE Microplastic exposure Nanoplastics

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.