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Exercise and nutrition may keep your cells young, study suggests

NCT ID NCT07479940

Knowledge-focused Sponsor: University of Sao Paulo Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at how nutritional counseling and exercise affect telomeres—the protective caps on our chromosomes that shorten as we age—in elderly women. Researchers will compare women with and without obesity, measuring changes in telomere length and other aging markers after 9 weeks of diet advice and 20 weeks of combined aerobic and strength training. The goal is to understand whether lifestyle changes can slow cellular aging.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nutritional counseling and combined physical training (aerobic and strength exercises)
What this could lead to
If successful, this could reveal how diet and exercise slow cellular aging, pointing toward lifestyle recommendations for healthier aging.
What could go wrong
This is an early-stage observational study with only 60 participants, so results may not apply broadly. It measures biological markers, not disease outcomes, so real-world benefits remain uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 75 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * being female; * between 60 and 75 years old; * a BMI between 22 and 40 kg/m²; * being sedentary (not exercising for at least 3 months). Exclusion Criteria: * a history of cancer, autoimmune or neurodegenerative diseases; * excessive alcohol consumption; * smoking * score ≤13 on the Mini-Mental State Examination (MMSE).

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Conditions

The condition(s) this trial relates to.

Inflammation inflammatory disease Motor Activity nutritional disorder Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging Exercise Inflammation Nutrition Obesity Oxidative DNA damage Oxidative stress Telomere shortening

Contacts and locations

Locations

  • Universidade de São Paulo - Escola de Educação Fisica e Esporte

    Ribeirão Preto, São Paulo, 14040-907, Brazil

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