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Gum treatment may unlock heart health secrets

NCT ID NCT07591844

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a deep dental cleaning (called non-surgical periodontal therapy) can change levels of a substance called asprosin in the blood of people who have both stable angina and gum disease. Asprosin is a protein that may play a role in heart health and inflammation. Researchers will measure asprosin before and three months after the cleaning in 60 adults to see if there is a connection.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Non-surgical periodontal therapy (deep dental cleaning)
What this could lead to
If successful, this could reveal a biological link between gum treatment and heart health, pointing toward new ways to manage stable angina.
What could go wrong
This is a small, early study with only 60 participants and no control group, so results may not be conclusive or widely applicable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Willingness to participate in the study and provide written informed consent * Age 18 years or older * No periodontal treatment within the past 6 months * No use of local or systemic antibiotics within the past 3 months Exclusion Criteria: * Unwillingness to participate in the study or to provide informed consent * Age under 18 years * Use of local or systemic antibiotics for the treatment of widespread infection within the past 3 months * Receipt of periodontal treatment within the past 6 months * Pregnancy or lactation (for female participants) * History of acute myocardial infarction within the past 6 months

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Conditions

The condition(s) this trial relates to.

Angina, Stable Arachnodactyly cardiovascular disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    1 site. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ondokuz Mayis University

    Samsun, Atakum, 55270, Turkey (Türkiye)

    Contact Email: •••••@•••••

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