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Can a natural supplement keep your blood vessels young?

NCT ID NCT07469475

Disease control Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a daily supplement made from ginger, L-citrulline, and two herbs can improve blood vessel function and reduce markers of aging in healthy adults. Over six weeks, 35 participants will take the supplement and have blood drawn to measure changes in PAI-1, a protein linked to aging and heart disease. The goal is to see if this natural approach can help prevent or delay cardiovascular problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dietary supplement containing ginger extract, L-citrulline, Paullinia cupana, and muira puama
What this could lead to
If it works, this could point toward a simple supplement to help maintain blood vessel health and reduce cardiovascular risk as people age.
What could go wrong
This is a very small, early-phase trial with only 35 participants and no placebo group. The supplement may not show meaningful effects on aging or disease risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

About 35 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * People of any gender at least 18 years of age who do not have a history of acute or chronic cardiovascular illnesses are eligible. Exclusion Criteria: * Younger than 18 years of age * Currently pregnant (which will be confirmed by pregnancy test for participants capable of pregnancy) * Using hormonal birth control * Current smoker * Allergy to ginger, muira puama, Paullinia cupana, or L-citrulline * Previous use of Revactin® or RM * History of serious cardiovascular events, including myocardial infarction (heart attack) or stroke * History of coronary, cardiac, or carotid surgery such as a stent, heart surgery, or endarterectomy * Active cancer of any type other than skin cancer

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging Endothelial dysfunction Senescence

Contacts and locations

Locations

  • UCLA

    Los Angeles, California, 90034, United States

  • UCLA The Men's Clinic

    Santa Monica, California, 90403, United States

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