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Mind over migraine? brain scans may reveal who benefits from meditation

NCT ID NCT02145117

Knowledge-focused Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study looks at whether brain scans can show changes in veterans with post-traumatic headaches after they complete a 9-week mindfulness-based stress reduction (MBSR) program. The goal is to find brain markers that might predict who improves. Veterans with mild post-traumatic headaches will be asked to undergo brain imaging and participate in MBSR training. The study also checks if it's feasible for veterans to complete the training and scans.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mindfulness-Based Stress Reduction (MBSR) training
What this could lead to
If brain scans can predict who benefits from mindfulness training, it could lead to more personalized care for veterans with post-traumatic headaches.
What could go wrong
This is a small, early study, so results may not apply to everyone. Brain imaging biomarkers are still experimental and may not reliably predict treatment response.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

21 people

The number who actually took part.

Started

Sep 2013

Finished

Apr 2016

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Males and female veterans at least 18 years of age * Mild post traumatic headaches, diagnosed by a physician * No prior training in MBSR or other mindfulness or meditation training will be allowed * Able to read and speak English * No participation in a clinical trial within the last 28 days Exclusion Criteria: * Current severe psychiatric diagnoses (e.g., schizophrenia, bipolar disorder, claustrophobia, history of panic attacks) * Significant co-morbid condition(s) such as insulin-dependent diabetes, cancer, obesity (BMI\>35), severe lung disease, neurological conditions (e.g., seizures), uncontrolled hypertension, or significant heart disease * History of persistent headaches prior to TBI * Unsafe for MRI (e.g., metal objects/shrapnel, metallic implants, brain or skull abnormalities, and claustrophobia) * Use of centrally acting medications that will interfere with the neuroimaging testing (e.g. narcotic medications) * Daily use of illicit drugs or marijuana * Daily alcohol consumption of greater than 2 units

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Conditions

The condition(s) this trial relates to.

Post-Traumatic Headache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post-traumatic headache

Contacts and locations

Locations

  • VA West Los Angeles Medical Center

    Los Angeles, California, 90073, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.