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Can magnetic pulses ease Post-Concussion headaches?

NCT ID NCT05857761

Symptom relief Sponsor: University of Aarhus Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at why some people get persistent headaches after a mild concussion and tests a new treatment called repetitive transcranial magnetic stimulation (rTMS). Researchers will measure headache days and blood markers in 62 adults who had a mild brain injury 2-4 months earlier. Half will receive real rTMS and half a sham version to see if it reduces headache severity.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
repetitive transcranial magnetic stimulation (rTMS)
What this could lead to
If successful, rTMS could offer a new, non-drug treatment to reduce headache days after a mild concussion.
What could go wrong
This is a small, early-stage study with only 62 participants, and the results may not apply to everyone. rTMS may not work better than a sham procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

62 people

The number who actually took part.

Started

Aug 2023

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. mTBI within the last 2 to 4 months according to the diagnostic criteria recommended by the WHO task force 2. age ≥ 18 years at the time of mTBI 3. Rivermead Post-Concussion Symptoms Questionnaire (RPQ) score ≥ 3 (moderate or severe problem) for subitem headache and a diagnosis of persistent PTH attributed to mTBI according to ICHD-3. Additionally, for study 2 and 3, subjects have to be stable on preventative headache medication. However, subjects are permitted to take ''as needed'' (PRN) medications throughout the study with documentation in a daily headache diary. Exclusion Criteria: 1. objective neurological findings and/or acute trauma CT scan indicating neurological disease or brain damage 2. previous mTBI within the last 2 years years leading to PCS lasting ≥ 3 months. Additionally, for study 2 and 3, 3. Pre-trauma headache frequency ≥ 10 days in average per month the last 3 months prior to mTBI. 4. past history of TMS therapy or TMS-related contraindications (pacemaker, epilepsy etc.).

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Conditions

The condition(s) this trial relates to.

Brain Concussion Post-Traumatic Headache traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Concussion, mild Mtbi - mild traumatic brain injury Post-traumatic headache

Contacts and locations

Locations

  • Reseach Unit Hammel Neurocenter

    Hammel, 8450, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.