Special camera peers inside airways to reveal COVID-19's effect on lung blood vessels
NCT ID NCT04884061
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study uses a special bronchoscopy technique called narrow band imaging to look at blood vessel patterns in the airways of people with COVID-19. Researchers will compare images from three groups: patients with COVID-19, patients with other lung infections, and patients with lung nodules. The goal is to see if COVID-19 causes unique changes in the tiny blood vessels of the bronchial tree.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If distinct vessel patterns are found, this could help doctors better understand how COVID-19 affects the lungs and possibly guide future diagnosis or treatment.
- What could go wrong
- This is a small, observational study with only 30 participants. It describes patterns but does not test any treatment, so it may not lead to direct clinical changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
30 people
The number who actually took part.
- Started
-
May 2021
- Expected to finish
-
Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
\- Patients who undergo bronchoscopy with image and/or videos recording of NBI aspect of the proximal bronchial tree (carina, right and left upper lobe). Three groups of patients will be selected: 1) Patients hospitalized with SARS-CoV2 infection proven by RT-PCR test ; 2) patients hospitalized with lower respiratory tract infections unrelated to SARS-CoV2 (RT-PCR negative for SARS-CoV2) ; 3) Patients who have had bronchoscopy performed as part of the assessment of a distal pulmonary nodule (RT-PCR negative for SARS-CoV2).
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients who undergo bronchoscopy with image and/or videos recording of NBI aspect of the proximal bronchial tree (carina, right and left upper lobe). * Patients hospitalized with SARS-CoV2 infection proven by RT-PCR test * patients hospitalized with lower respiratory tract infections unrelated to SARS-CoV2 (RT-PCR negative for SARS-CoV2) * Patients who have had bronchoscopy performed as part of the assessment of a distal pulmonary nodule (RT-PCR negative for SARS-CoV2). Exclusion Criteria: * Patients under legal protection * Patients who refuses the use of his personal medical data
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Amiens
Amiens, 80480, France
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