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Promising PANDAS painkiller trial fizzles out

NCT ID NCT04015596

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 28 times

Summary

This study aimed to see if naproxen sodium, a common anti-inflammatory drug, could reduce obsessive-compulsive symptoms in children with PANDAS, a condition linked to strep infections. The trial planned to enroll children aged 6 to 15 with new-onset OCD, but was terminated early after only 2 participants. No results are available due to the small size.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

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