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Can a gentle electrical current quiet Obsessive-Compulsive symptoms?

NCT ID NCT03304600

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 09, 2026 · Last updated Sep 10, 2026 · Updated 1 time

Summary

Researchers are testing transcranial direct current stimulation (tDCS), a non-invasive technique that applies a weak electrical current to the scalp, in adults with severe obsessive-compulsive disorder that has not improved with at least two antidepressants. The study compares active tDCS with a sham version over two weeks. The main goal is to see whether OCD symptom scores drop more with the real treatment than with the sham.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation, a gentle electrical current applied to the scalp
What this could lead to
If it works, tDCS could offer a non-invasive option for people with severe OCD that has not improved with standard drugs.
What could go wrong
This is a mid-stage trial, so results may not hold up in larger studies. tDCS can cause mild scalp tingling or headache, and some participants receive a sham treatment that delivers no active current.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

83 people

The number who actually took part.

Started

Nov 2017

Finished

Feb 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Meets criteria for obsessive compulsive disorder according to Diagnostic and Statistical Manual (DSM IV) with a "good insight" (BABS) * No current depressive and suicidal risks * No epileptic pathology * Age: Participants will be both males and females, 18-70 years of age included. * Chronic Obsessive compulsive disorder ( Total Y-BOCS\>20 or Y-BOCS one subscale \> 15) * Obsessive compulsive disorder resistant to pharmacology treatment : 1. at least 2 antidepressants (IRS type) (\> 12 weeks) 2. cognitive and comportment therapy since at least one year * Treatment stability (antidepressants) for more than 12 weeks without significant improvement. * Affiliation to a social security system (recipient or assignee), * Signed written inform consent form Exclusion Criteria: * Female subject who is pregnant, or of child-bearing age, sexually active and not using reliable contraception or who is nursing, * Patient under curators * Patient hospitalized under duress * Meets another diagnosis of axe 1 of DSM-IV * Current depressive or suicidal risks * Patient with any form of metal in the cranium, a pacemaker, skull defects, or skin lesions to the scalp (cuts, abrasions, rash) * Epileptic patient * Patient with a medical history of cranial trauma * Patient unable to give his or hers informed consent

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • C.H. Guillaume Regnier

    Rennes, 35703, France

  • CHU de Nantes

    Nantes, 44093, France

  • Centre Hospitalier Henri Laborit

    Poitiers, 86021, France

  • Hospices Civils De Lyon

    Lyon, France

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