New combo surgery for obesity and reflux tested – but study stopped early
NCT ID NCT04626232
First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 29 times
Summary
This study aimed to compare a standard sleeve gastrectomy (removing part of the stomach) with a modified version called N-Sleeve, which adds a wrap around the top of the stomach to prevent acid reflux. The trial was designed for people with severe obesity and GERD, but only 2 patients enrolled before the study was terminated. Because it stopped so early, we cannot draw any meaningful conclusions about which surgery might be better.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU Montpellier
Montpellier, 34295, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
surgical procedure (N-Sleeve: sleeve gastrectomy with Nissen fundoplication)
What this could lead to
If successful, the N-Sleeve technique could reduce acid reflux after weight-loss surgery, potentially improving quality of life for people with severe obesity and GERD.
What could go wrong
The trial was terminated early with only 2 participants, so no reliable conclusions can be drawn. The added procedure may also carry extra surgical risks.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.