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Strumming for the brain: could ukulele lessons sharpen minds in MS?

NCT ID NCT07759115

Symptom relief Sponsor: University of Texas at Austin Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 12, 2026 · Last updated Aug 18, 2026 · Updated 3 times

Summary

This study tests whether a 12-week online ukulele learning program, called Music-4-MS, can improve cognitive function in people with multiple sclerosis (MS). Half the participants will learn to play the ukulele, while the other half will simply listen to music they enjoy. The goal is to see if this music-based approach is feasible and acceptable, and whether it might support thinking and emotional well-being.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A 12-week online ukulele learning program (Music-4-MS) compared to passive music listening.
What this could lead to
If feasible and effective, this could offer a new, engaging way to support cognitive health in people with MS.
What could go wrong
This is a small feasibility study, so it may not show clear cognitive benefits. Results may not generalize to all people with MS.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 64 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Aug 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed with multiple sclerosis (relapsing remitting, secondary progressive, primary progressive) * Diagnosed more than 6 months prior to starting study * Self-reported cognitive impairment as assessed by having at leased 5 problems "sometimes" or more often on the Perceived Deficits Questionnaire * Read, write, and understand English * Access to internet Exclusion Criteria: * Diagnosed with another neurological condition that causes cognitive impairment * MS exacerbation within the last 30 days * Professional musician (primary source of income)

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Conditions

The condition(s) this trial relates to.

autoimmune disease autoimmune disorder of the nervous system CNS demyelinating autoimmune disease demyelinating disease immune system disorder multiple sclerosis nervous system disorder Pathologic Processes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Autoimmune diseases Autoimmune diseases of the nervous system Demyelinating autoimmune diseases, CNS Demyelinating diseases Immune system diseases Multiple sclerosis Nervous system diseases Pathologic processes

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Texas at Austin

    RECRUITING

    Austin, Texas, 78712, United States

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