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Knee pain relief showdown: mulligan technique vs ultrasound gel

NCT ID NCT07445607

Symptom relief Sponsor: Ahram Canadian University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two physical therapy treatments for patellofemoral pain syndrome, a common cause of knee pain. Forty-five participants will be randomly assigned to receive either Mulligan mobilization with movement, phonophoresis with chitosan gel, or standard exercises for 4 weeks. The goal is to see which treatment best improves neuromuscular control and reduces pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
chitosan gel
What this could lead to
If successful, this could point to a more effective physical therapy approach for managing chronic knee pain and improving function.
What could go wrong
This is a small, early-stage trial with only 45 participants, so results may not apply to everyone. The treatments are non-invasive but may not work for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 45 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Insidious onset of anterior knee pain * Retro patellar or peripatellar pain * Pain duration more than four weeks (chronic/subacute) * Pain severity ≥ 3/10 on Visual Analog Scale (VAS) * Pain during at least two of the following activities: stair ascent or descent, squatting, prolonged sitting (theater sign), or kneeling * Positive patellar compression test (pain reproduced by compressing the patella into the trochlear groove) * Patellar tenderness along the medial or lateral borders * Age between 18 and 35 years * Baseline Kujala score (Arabic version): approximately 67-71 (indicating moderate to severe dysfunction) Exclusion Criteria: * Traumatic injury (e.g., dislocation, fracture, ligament or meniscus pathology) * Inflammatory arthritis (e.g., rheumatoid arthritis, gout) * Prior knee surgery * Current use of NSAIDs or corticosteroids

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Conditions

The condition(s) this trial relates to.

patellofemoral pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Patellofemoral pain syndrome

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ahram Canadian unveracity

    Cairo, Giza Governorate, 12573, Egypt

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