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Can hard knee exercises reveal how patellofemoral pain changes movement?
NCT ID NCT07812519
First seen Sep 10, 2026 · Last updated Sep 11, 2026 · Updated 1 time
Summary
Researchers want to understand how people with patellofemoral pain respond to resistance training taken to muscular failure. About 30 participants aged 15 to 35 with pain in one knee will perform a knee exercise until they cannot continue or their pain reaches a moderate level. The team will record pain ratings and use cameras and force plates to analyze knee and hip motion during the exercise. The study observes responses rather than testing a treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- resistance training to muscular failure
- What this could lead to
- If researchers learn how pain and movement change during hard knee exercises, this could help physiotherapists set safer training targets for people with patellofemoral pain.
- What could go wrong
- This is a small observational study of 30 people, so it cannot prove that resistance training treats or worsens knee pain. Participants stop if pain reaches a moderate level, and the findings may not apply to other age groups or knee conditions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2026
An estimate. Start dates often move.
- Expected to finish
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May 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This project will include patients diagnosed with PFP (ICD-10: M22.2).
- Ages
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15 to 35 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients diagnosed with PFP in only one knee by a licensed healthcare professional. * Aged 15-35 years. * A physical activity level of 3/10 or higher on the Tegner Activity Scale before the injury. Exclusion Criteria: * Any prior injury or condition with residual symptoms that may affect the results. * Current injury or condition affecting the performance of the test. * Resting pain greater than 0-1/10 on the Numeric Pain Rating Scale (NRS) and pain greater than 1-2/10 during light daily activities such as walking, sitting, standing, or climbing stairs.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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