A simple hip exercise may boost knee pain recovery — trial puts it to the test
NCT ID NCT07730437
First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time
Summary
This trial tests whether adding clamshell exercises — a hip-strengthening move — to standard physical therapy can better reduce pain and improve knee function in people with patellofemoral pain syndrome (pain around the kneecap). Forty adults aged 18 to 45 with this common knee condition will be randomly assigned to receive either standard therapy alone or standard therapy plus clamshell exercises. Both groups attend supervised sessions three times a week for four weeks. Researchers will measure changes in pain and knee function to see if the extra exercise makes a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- clamshell exercises added to standardized physical therapy
- What this could lead to
- If it works, this could point toward a simple, low-cost addition to physical therapy that improves recovery from common knee pain.
- What could go wrong
- This is a small, early trial with only 40 participants, so results may not apply to everyone. The added benefit of clamshell exercises may be small or none.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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Jan 2026
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 45 years. Male or female participants. Clinically diagnosed with patellofemoral pain syndrome (PFPS) according to the American Physical Therapy Association (APTA) clinical practice guidelines. Presence of retropatellar or peripatellar pain. Reproduction of retropatellar or peripatellar pain during squatting or other functional activities that load the patellofemoral joint in knee flexion. Symptoms present for at least 3 months. Pain intensity of ≥3 on the Numeric Pain Rating Scale (NPRS) during aggravating activities. Able and willing to provide written informed consent and comply with the study procedures. Exclusion Criteria: * History of knee surgery, ligament injury, meniscal tear, patellar dislocation, or knee osteoarthritis. Lumbar radiculopathy, hip pathology, or systemic inflammatory arthritis (e.g., rheumatoid arthritis). Corticosteroid injection or knee surgery within the previous 3 months. Neuromuscular disorders affecting muscle function (e.g., stroke or Parkinson's disease). Pregnancy or within 6 months postpartum. Family history of early degenerative joint disease. Any condition that, in the investigator's opinion, would interfere with safe participation or completion of the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tahir general Hospital Charsadda
Charsadda, KPK, 24420, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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