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App-Based therapy aims to tackle knee pain without pills

NCT ID NCT07769593

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 18, 2026 · Last updated Aug 19, 2026 · Updated 1 time

Summary

This study tests whether a digital therapeutic called MORA Cure can reduce knee pain in adults over 50 with knee osteoarthritis and anterior knee pain. Participants use a mobile app for 8 weeks that provides personalized exercises and cognitive behavioral therapy content. The app also tracks symptoms and movement to adjust the program. The goal is to see if this app-based approach improves pain and function, offering a potential non-drug option for managing osteoarthritis.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
MORA Cure, a digital therapeutic app providing personalized rehabilitation exercises and cognitive behavioral therapy content
What this could lead to
If effective, MORA Cure could offer a non-drug, app-based way to reduce knee pain and improve function in people with osteoarthritis, potentially delaying or avoiding surgery.
What could go wrong
This is a small pilot study without a control group, so results may not be conclusive. The app's benefits could be modest, and not everyone may find it easy to use or adhere to the exercise regimen.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 44 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

51 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adults older than 50 years. 2. Kellgren-Lawrence grade 1 or higher on weight-bearing plain radiographs of the study knee. 3. Osteoarthritis-related pain in the study knee for at least 3 months. 4. Anterior knee pain in the study knee involving the peripatellar, anterior patellar, or retropatellar region, with clear provocation or worsening of anterior knee pain during at least one patellofemoral joint-loading activity: stair ascent or descent, squatting, or rising from a chair. 5. If medial, lateral, or posterior knee pain is also present, the participant is able to distinguish and separately report anterior knee pain. 6. Voluntary written informed consent before study participation. Exclusion Criteria: 1. Acute injury of the study knee within the previous 3 months, including fracture, ligament tear, or meniscal tear requiring surgical treatment or immobilization. 2. Injection therapy to the study knee within the previous 3 months. 3. Current use of opioid analgesics for pain control. 4. Does not own a smartphone or is unable to use the mobile application. 5. Current participation in another clinical trial or planned participation in another clinical trial during this study. 6. Diagnosed active inflammatory arthritis, including rheumatoid arthritis, psoriatic arthritis, or reactive arthritis. 7. Acute attack of gout or pseudogout in the study knee within the previous 3 months. 8. Previous total knee arthroplasty, corrective osteotomy, or other major surgery affecting knee alignment or joint structure in the study knee. 9. Any other condition that, in the investigator's judgment, makes the participant unsuitable for the study.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHA Bundang Medical Center

    Seongnam-si, Gyeonggi-do, 13496, South Korea

  • SMG-SNU Boramae Medical Center

    Dongjak, Seoul, 07061, South Korea

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