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Tiny molecules in artery plaques may reveal stroke clues

NCT ID NCT03149406

Knowledge-focused Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study analyzed microRNAs in carotid artery plaques from 30 patients who had surgery to remove them. Researchers compared plaques from people who had already had a stroke (symptomatic) with those who had not (asymptomatic) to see if certain microRNAs are linked to stroke risk. The goal was to better understand why some plaques cause strokes and others do not.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could point toward new ways to predict stroke risk or develop treatments for carotid artery disease.
What could go wrong
This is a very small, early-stage observational study with only 30 participants. It does not test any treatment, so any potential applications are far off and uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

30 people

The number who actually took part.

Started

Dec 2012

Finished

Dec 2015

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Symptomatic patients in the service, and asymptomatic in consultation with carotid atheroma plaque

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Any adult with a carotid thrombo endarterectomy, * affiliated to a social security scheme, * informed of the study and not opposed to it. Exclusion Criteria: * Any person benefiting from an iterative carotid surgery, * or refusing to participate in the study, * or not being able to express its consent.

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Conditions

The condition(s) this trial relates to.

carotid stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carotid plaque MIRNAS

Contacts and locations

Locations

  • CHU Amiens Picardie

    Amiens, Picardie, 80054, France

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