Gut microbiome may hold key to personalized Crohn's therapy
NCT ID NCT06453720
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 34 times
Summary
This study looks at whether the unique mix of bacteria and fungi in the gut can predict how well Crohn's disease patients will respond to treatment. Researchers will collect stool, blood, and tissue samples from 100 adults during routine colonoscopies and track their health for a year. The goal is to find microbial signatures that could one day help doctors choose the most effective therapy for each patient.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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GI Research Institute
RECRUITINGVancouver, British Columbia, V6Z 2K5, Canada
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors predict which treatments will work best for individual Crohn's disease patients based on their gut microbiome.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test a new therapy. The findings may not lead to immediate clinical changes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.