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New hope for women with severe vulvar skin disease: methotrexate trial launches

NCT ID NCT07352917

First seen Jan 24, 2026 · Last updated May 25, 2026 · Updated 23 times

Summary

This study tests if methotrexate, an immune-modulating drug, can help women with severe vulvar lichen sclerosus who did not get better with standard steroid creams. Twelve women will receive weekly injections for 12 months. The goal is to see if symptoms and skin changes improve, and if the treatment is safe and tolerable.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • DermoCentro

    RECRUITING

    São José dos Campos, São Paulo, 12245760, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.