New radiation drug targets Hard-to-Treat cancers in early trial
NCT ID NCT07213791
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 24 times
Summary
This early-phase study tests a new drug, LY4337713, that delivers radiation directly to cancer cells with a specific protein called FAP. It is for adults with advanced or spread cancers like pancreatic, breast, ovarian, or colorectal cancer that have not responded to other treatments. The main goals are to check safety, find the best dose, and see if the drug shrinks tumors. The study lasts about 5 years per person.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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Amsterdam UMC - Locatie VUmc
NOT_YET_RECRUITINGAmsterdam, 1081 HV, Netherlands
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BAMF Health Inc.
RECRUITINGGrand Rapids, Michigan, 49503, United States
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Barbara Ann Karmanos Cancer Institute
NOT_YET_RECRUITINGDetroit, Michigan, 48201, United States
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Baylor College of Medicine
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
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Beth Israel Deaconess Medical Center
NOT_YET_RECRUITINGBoston, Massachusetts, 02215, United States
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Biogenix Molecular, LLC
RECRUITINGMiami, Florida, 33165, United States
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David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center
NOT_YET_RECRUITINGNew York, New York, 10065, United States
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Duke University Medical Center
RECRUITINGDurham, North Carolina, 27710, United States
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Erasmus MC
NOT_YET_RECRUITINGGE Rotterdam, 3015, Netherlands
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Fox Chase Cancer Center
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19111, United States
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Hoag Memorial Hospital Presbyterian
RECRUITINGNewport Beach, California, 92663, United States
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Indiana University (IU) School of Medicine
RECRUITINGIndianapolis, Indiana, 46202, United States
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Kyoto University Hospital
NOT_YET_RECRUITINGKyoto, 606-8507, Japan
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Maastricht University Medical Center
NOT_YET_RECRUITINGMaastricht, 6229 HX, Netherlands
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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Mayo Clinic - Rochester
NOT_YET_RECRUITINGRochester, Minnesota, 55905, United States
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Moffitt
NOT_YET_RECRUITINGTampa, Florida, 33612, United States
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Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis (NKI-AVL)
NOT_YET_RECRUITINGAmsterdam, 1066 CX, Netherlands
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New York University (NYU) Clinical Cancer Center
NOT_YET_RECRUITINGNew York, New York, 10016, United States
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Stanford University Medical Center
RECRUITINGStanford, California, 94305, United States
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Stichting Radboud Universitair Medisch Centrum
NOT_YET_RECRUITINGNijmegen, 6525 GA, Netherlands
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Texas Oncology - DFW (Sammons CC)
NOT_YET_RECRUITINGDallas, Texas, 75246, United States
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United Theranostics
NOT_YET_RECRUITINGGlen Burnie, Maryland, 21061, United States
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Universitaetsklinikum Essen
NOT_YET_RECRUITINGEssen, 45147, Germany
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Universitair Medisch Centrum Utrecht
NOT_YET_RECRUITINGUtrecht, 3584CX, Netherlands
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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University of Wisconsin - Carbone Cancer Center
RECRUITINGMadison, Wisconsin, 53792, United States
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Washington University School of Medicine in St. Louis
NOT_YET_RECRUITINGSt Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.