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New drug targets tough cancers in early trial

NCT ID NCT06238479

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 23 times

Summary

This early-phase study tests a new drug called LY4101174 in people with advanced solid tumors that have come back or spread. The drug is designed to deliver a cancer-killing agent directly to tumor cells. The main goals are to check safety, find the right dose, and see if it shrinks tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AdventHealth Orlando

    Orlando, Florida, 32804, United States

  • Austin Health

    Heidelberg, 3084, Australia

  • CHU Strasbourg-Hautepierre

    Strasbourg, 67098, France

  • Centre Leon Berard

    Lyon, 69373, France

  • Centre Oscar Lambret

    Lille, 59020, France

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Gustave Roussy

    Villejuif, 94805, France

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Virgen Del Rocio

    Seville, 41013, Spain

  • Hunan Cancer Hospital

    Changsha, 410013, China

  • Icon Cancer Centre Kurralta Park

    Kurralta Park, 5037, Australia

  • Institut Jules Bordet

    Anderlecht, 1070, Belgium

  • Institut Paoli-Calmettes

    Marseille, 13273, France

  • Kyoto University Hospital

    Kyoto, 606-8507, Japan

  • Laura & Isaac Perlmutter Cancer Center at NYU Langone Health

    New York, New York, 10016, United States

  • MD Anderson Cancer Center

    Madrid, 28033, Spain

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • National Cancer Center Hospital

    Chūōku, 104-0045, Japan

  • National Cancer Center Hospital East

    Kashiwa, 277-8577, Japan

  • Peking University First Hospital

    Beijing, 100034, China

  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island

    Mineola, New York, 11501, United States

  • Shanghai East Hospital

    Shanghai, 200433, China

  • South Texas Accelerated Research Therapeutics (START)

    San Antonio, Texas, 78229-3307, United States

  • The Cancer Institute Hospital of JFCR

    Kōtō City, 135-8550, Japan

  • UT Southwestern Medical Center

    Dallas, Texas, 75390-8884, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.