Does anesthesia flow rate affect inflammation in obesity surgery?
NCT ID NCT07230704
First seen Jun 27, 2026 · Last updated Aug 28, 2026 · Updated 3 times
Summary
This study looked at 155 adults who had weight-loss surgery to see if using a low-flow or standard-flow anesthesia gas changed inflammation levels in the body. Researchers measured blood markers like CRP before and after surgery. The goal was to learn more about how anesthesia affects the body, not to test a new treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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155 people
The number who actually took part.
- Started
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Jan 2022
- Finished
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Jan 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Retrospective analysis of 155 adult patients who underwent laparoscopic sleeve gastrectomy under general anesthesia between January 2022 and January 2025 at Adana City Training and Research Hospital. Patients were grouped according to the fresh gas flow rate used during anesthesia (low-flow vs. standard-flow sevoflurane).
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients aged 18-60 years * Underwent laparoscopic sleeve gastrectomy under general anesthesia * Received low-flow or standard-flow sevoflurane anesthesia * ASA physical status I-III * Complete perioperative records available Exclusion Criteria: * Conversion to open surgery * Incomplete or missing data * Significant comorbidities (e.g., severe cardiac, hepatic, or renal dysfunction) * Perioperative complications unrelated to anesthesia * Age \<18 or \>60 years
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Adana City Training and Research Hospital
Adana, Adana, 010650, Turkey (Türkiye)
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