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Could a green dye and laser light save your gums?

NCT ID NCT07609888

Disease control Sponsor: Gulf Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding a light-based antibacterial treatment called photodynamic therapy (PDT) to standard deep cleaning improves gum health in people with moderate gum disease. Thirty adults received standard cleaning on one side of the mouth and standard cleaning plus PDT on the other. PDT uses a green dye and a special laser to kill leftover bacteria without antibiotics. The study measured gum pocket depth, gum attachment, and bleeding at the start and after 3 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Indocyanine green dye and 810 nm diode laser (photodynamic therapy)
What this could lead to
If it works, this could offer a simple, antibiotic-free way to boost the effectiveness of standard gum disease treatment and reduce the need for further procedures.
What could go wrong
This is a small, completed study with only 30 participants, so results may not apply to everyone. The added benefit of light therapy over standard cleaning alone may be modest or not clinically significant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Jun 2023

Finished

Jun 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \- Adults aged 18 years and older * Diagnosis of Stage II periodontitis according to the 2018 classification of the World Workshop of Periodontology (AAP/EFP) * At least two non-adjacent sites with interproximal probing pocket depth of 4-5 mm * Interproximal clinical attachment loss of 3-4 mm at affected sites * Willing and able to provide written informed consent Exclusion Criteria: * Periodontal therapy including scaling and root debridement within the last 12 months * Antibiotic use or regular use of mouthwash in the 3 months prior to enrollment * Pregnancy * Any systemic condition that may affect periodontal healing (e.g. uncontrolled diabetes, immunocompromised states) * Regular use of hormonal contraceptives * Smoking more than 10 cigarettes per day

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Conditions

The condition(s) this trial relates to.

chronic periodontitis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic periodontitis (disorder) Periodontitis

Contacts and locations

Locations

  • Thumbay University Hospital, Postgraduate Research Centre

    Ajman, United Arab Emirates

More trials for these conditions

Other studies related to the condition(s) this trial covers.