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Laser boosts gum healing in smokers with deep pockets

NCT ID NCT07213752

Disease control Sponsor: Selcuk University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding a diode laser to standard deep cleaning helps smokers with severe gum disease. 33 smokers were split into two groups: one got standard cleaning alone, the other got cleaning plus laser. After 3 months, the laser group had shallower gum pockets, less inflammation, and lower oxidative stress markers. The laser appears to enhance gum healing in smokers, who often heal poorly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

33 people

The number who actually took part.

Started

Dec 2023

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * no periodontal treatment within the previous 6 months; * no use of antibiotics within the previous 3 months; * no systemic disease and alcohol drinkers, or drug users; * no use of anti-inflammatory drugs within the past 3 months; * no pregnancy; * no use of hormonal contraceptives; and * current smokers with a history of smoking ≥10 cigarettes per day for at least one year. Exclusion Criteria: * Patients with \<20 teeth, grade III tooth mobility, partial dentures, or fixed prostheses were excluded. Additionally, those with dental implants or peri-implant diseases were also excluded.

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Conditions

The condition(s) this trial relates to.

periodontal disorder periodontitis Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diode laser therapy Malondialdehyde Periodontal disease Periodontitis Periodontitis stage III Smoking

Contacts and locations

Locations

  • Selcuk University Faculty of Dentistry Department of Periodontology

    Konya, Selçuklu, 42250, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.