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Laser acupuncture may ease common knee pain without drugs

NCT ID NCT07655258

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates whether high-intensity laser acupuncture, combined with exercise, can reduce pain and improve knee function in people aged 18 to 25 with patellofemoral pain syndrome (front knee pain). Participants receive either real laser acupuncture or a sham laser, plus a standard exercise program, over four weeks. The goal is to see if the laser adds extra benefit for pain relief, daily function, and satisfaction.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
high-intensity laser acupuncture
What this could lead to
If effective, this approach could offer a non-invasive, drug-free option for reducing knee pain and improving function in young adults with patellofemoral pain syndrome.
What could go wrong
This is a small, early-stage trial with 60 participants, so results may not apply to everyone. The sham laser group also receives exercise, making it hard to isolate the laser's true effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 25 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with patellofemoral pain syndrome (positive Clarkes sign and Waldron test) * Age from 18 to 25 years * Patients suffering from pain which aggravated by prolonged sitting, stair climbing, running, squatting, kneeling, hopping\\jumping, overuse activities and relieved by rest for at least 3 months * Visual analog scale (VAS) greater than 3 points in daily activity * The ability to participate in the study and follow the treatment schedule. Exclusion Criteria: * Physiotherapy in the last 12 months * Intra-articular injection in the last 3 months * Other knee disorders such as: (osteoarthritis, previous knee surgery, history of knee arthroplasty, or traumatic injury related joint deformity) * BMI greater than or equal 30 * Pregnancy * Pacemaker insertion * Photosensitivity * History of using oral analgesic or NSAIDs in the previous 4 weeks, * History of malignancy, psychiatric disorder, mental retardation, neurologic dysfunction, diabetes mellitus, or uncontrolled hypertension.

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Conditions

The condition(s) this trial relates to.

patellofemoral pain syndrome Patient Satisfaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Patellofemoral pain syndrome

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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