Double nerve block may cut opioid use after knee surgery
NCT ID NCT06952556
First seen Mar 13, 2026 · Last updated Jun 22, 2026 · Updated 20 times
Summary
This study tests whether adding an extra nerve block (IPACK) to a standard one (adductor canal block) can better control pain and reduce opioid use after knee realignment surgery. About 100 adults undergoing specific knee osteotomies will be randomly assigned to receive either the standard block alone or the standard block plus the IPACK block. The main goal is to measure how much opioid pain medication they need in the first 24 hours after surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bupivacaine
What this could lead to
If successful, this could lead to a standard pain management approach that reduces opioid use after knee osteotomy surgery.
What could go wrong
This is a small, single-center study. The added block may not provide significant extra pain relief, and there is always a risk of side effects from the nerve blocks.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.