Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Knee cartilage repair: can ACI surgery get you moving again?

NCT ID NCT06921889

Knowledge-focused Sponsor: University of Manchester Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 47 adults who are scheduled for autologous chondrocyte implantation (ACI) to repair knee cartilage injuries. Researchers will measure knee movement, balance, and walking ability before surgery and again 6 months after. The goal is to understand how knee function changes after ACI and help set realistic expectations for recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Autologous Chondrocyte Implantation (ACI) - a procedure using the patient's own cartilage cells to repair knee cartilage damage.
What this could lead to
If successful, this study could help doctors and patients know what to expect after ACI surgery and identify common problems that physiotherapy might fix.
What could go wrong
This is a small, observational study (47 people) that only follows patients for 6 months. It does not test a new treatment or prove long-term benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 47 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2024

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants undergoing ACI surgery for a chondral lesion in the knee.

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of a chondral injury to the knee by a consultant orthopaedic surgeon Participants must have this diagnosis, else they are not eligible for ACI surgery. * Listed for ACI for a chondral injury by a consultant orthopaedic surgeon Participants must be listed for ACI, as this is the treatment of interest in this research study * Over 18 years old Participants must be legally capable of providing informed consent for the study. Exclusion Criteria: * Listed for any treatment other than ACI Participants must be listed for ACI, as this is the treatment of interest in this research study * Under 18 years old. Participants must be legally capable of providing informed consent for the study.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Chondral defect are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

chondromalacia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chondral defect

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    7 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Addenbrooke's Hospital

    NOT_YET_RECRUITING

    Cambridge, CB2 0QQ, United Kingdom

  • Chapel Allerton Orthopaedic Centre

    RECRUITING

    Leeds, LS7 4SA, United Kingdom

  • New Cross Hospital

    RECRUITING

    Wolverhampton, WV10 0QP, United Kingdom

  • Royal National Orthopaedic Hospital

    RECRUITING

    Stanmore, HA7 4LP, United Kingdom

  • Royal Orthopaedic Hospital

    NOT_YET_RECRUITING

    Birmingham, B31 2AP, United Kingdom

  • Southampton General Hospital

    NOT_YET_RECRUITING

    Southampton, SO16 6YD, United Kingdom

  • Trafford General Hospital

    RECRUITING

    Manchester, M415SL, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.