Knee cartilage repair: your own cells could be the key
NCT ID NCT04296487
First seen Mar 20, 2026 · Last updated Jun 19, 2026 · Updated 16 times
Summary
This study is testing a procedure called autologous chondrocyte implantation (ACI) for people with knee cartilage defects. Doctors take a sample of the patient's own cartilage cells, grow them in a lab, and then implant them into the damaged area. The goal is to see if this approach is safe and effective at repairing the knee and improving function. The trial is currently recruiting 218 participants aged 15 to 50.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre Hospitalier Universitaire Vaudois - CHUV
RECRUITINGLausanne, Canton of Vaud, 1011, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
autologous chondrocytes (patient's own cartilage cells)
What this could lead to
If successful, this could offer a safe and effective way to repair knee cartilage damage, potentially reducing pain and improving mobility.
What could go wrong
This is an early-stage study focused on safety and feasibility. The procedure may not work for everyone, and risks include infection, inflammation, or incomplete healing.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.