Can a shot of your own blood cells boost hip surgery results?
NCT ID NCT03909139
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether adding platelet-rich plasma (PRP) or bone marrow aspirate concentrate (BMAC) to standard hip labral repair surgery helps people recover better. About 400 adults with hip labral tears will be randomly assigned to get surgery alone or surgery plus one of these cell-based treatments. The goal is to see if these additions improve hip function and slow down arthritis.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC)
- What this could lead to
- If it works, this could point toward a way to improve hip function and reduce arthritis progression after labral repair.
- What could go wrong
- This is an early-stage trial with 400 participants, so results may not apply to everyone. Adding PRP or BMAC may not provide extra benefit over standard surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 400 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2019
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This is a prospective study which will enroll adult subjects with evidence of an acetabular labrum tear. These subjects will be enrolled consecutively using the aforementioned criteria until we hit our enrollment of 300 subjects.
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria and Rationale: 1. Age 18 or older: patients of any age have the capacity to potentially benefit from labral repair 2. Symptoms consistent with a tear of the acetabular labrum (i.e., catching, clicking, popping, pain with sitting, episodic pain, pain with hip flexion, adduction, and/or internal rotation): asymptomatic labral tears do exist in the general population however there is not definitive evidence to suggest treatment of asymptomatic tears is beneficial. 3. Symptoms not due to some other acute process in or around the hip (including septic arthritis, osteonecrosis, hemarthrosis, iliotibial band syndrome, fractures of the femoral neck or head, fractures of the acetabulum, greater trochanteric pain syndrome, sacroiliac joint pain, piriformis syndrome, low back pain associated with hip pain and not knee nor acute low back injury): certain conditions are not treatable by either arthroscopy or physical therapy. Some of these conditions can be managed with physical therapy but not arthroscopy. 4. Availability of hip radiographs and magnetic resonance imaging (MRI and/or MRA): needed to assess eligibility 5. Evidence of labral tear on MRI and/or MRA: documentation of acetabular labrum tear 6. Willingness to participate and ability to understand and sign informed consent document: ability to understand study and consent willingly 7. Returning subjects enrolled in protocol 2017P001391/PHS Exclusion Criteria and Rationale: 1. Non-English speaking subjects: PROMs are only validated in English. 2. Systemic infection: surgery is generally contraindicated when systemic infection is present. 3. Systemic heparinization: the vascularity of the bone and adjacent tissues is significant, posing a potential problem for bleeding when the patient is anti-coagulated. 4. Pregnant women/fetuses: although surgery can be performed on pregnant women, pregnant women are excluded under federal regulations.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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MGH, Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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