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Blood marker may spot hidden fungal infections in ICU patients

NCT ID NCT03140748

Knowledge-focused Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether a substance called β-D-glucan in the blood can help identify and track fungal infections in the abdomen (peritonitis) in intensive care patients. Researchers measured levels in 70 adults with peritonitis, comparing those with and without Candida yeast. The goal was to see if this blood test could aid diagnosis and monitor treatment response.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could show that measuring β-D-glucan in the blood helps doctors diagnose and monitor fungal peritonitis, potentially improving treatment decisions.
What could go wrong
This is a small, observational study with only 70 participants. It does not test a treatment, so it may not lead to any direct patient benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

70 people

The number who actually took part.

Started

May 2018

Finished

Jun 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Major Patient (age ≥ 18 years) * Community or associated peritonitis, operated and hospitalized in resuscitation * Affiliation to a social security scheme Exclusion Criteria: * Allergy known to echinocandins * Dying Patient * Limitation of care * Predictable duration of follow-up ≤ 10 days * Transfusion within 3 months * Patient minor, patient under guardianship or curatorship

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Conditions

The condition(s) this trial relates to.

candidiasis infectious peritonitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Candida infection Peritonitis infectious

Contacts and locations

Locations

  • CHU Amiens Picardie

    Amiens, Picardie, 80054, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.