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Ketone power: could a drink boost recovery in extreme cycling?

NCT ID NCT06965491

Knowledge-focused Sponsor: KU Leuven Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether taking a ketone supplement after exercise and before sleep helps cyclists recover from physical and mental fatigue during a multi-day race. 18 experienced cyclists took part, and researchers measured muscle soreness, sleep quality, and thinking skills. The goal was to learn if this approach could improve recovery, not to treat a disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

18 people

The number who actually took part.

Started

Mar 2024

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 59 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * have been cycling consistently for at least 1 year before entry into the study * have been cycling for a minimum of 7 hours per week for the 6 months leading up to the study * additional for the field study: valid entry to the 2025 edition of the Absa Cape Epic * non-smoker Exclusion Criteria: * Do not follow a ketogenic diet or low-carbohydrate diet * Have any metabolic or auto-immune disease that will influence their metabolism * Take medication or supplements that is known to affect ketone supplement metabolism * suffering from a recurring injury or illness from which they have not fully recovered that is a contr-indication to perform high-intensity exercise * Unable to finish each stage * Women: if they are pregnant or breastfeeding

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Conditions

The condition(s) this trial relates to.

Fatigue Mental Fatigue

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endurance cycling performance Exogenous ketosis Fatigue, mental Fatigue; muscle, heart

Contacts and locations

Locations

  • KU Leuven

    Leuven, Vlaams-Brabant, 3000, Belgium

More trials for these conditions

Other studies related to the condition(s) this trial covers.