Fungal drug tested against deadly brain tumors
NCT ID NCT03796273
Summary
This early research study tested whether giving the antifungal drug ketoconazole for a few days before brain tumor surgery could affect tumor biology. The study involved 15 patients with either recurrent brain tumors (gliomas) or breast cancer that had spread to the brain. Researchers wanted to see if ketoconazole could block a specific protein (tGLI1) that might help tumors grow, and measure how much of the drug reached brain tissue.
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Locations
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Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157, United States
Conditions
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