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Brain drain: can shunt surgery reverse cognitive decline and frailty?
NCT ID NCT07642726
First seen Jun 27, 2026 · Last updated Sep 09, 2026 · Updated 2 times
Summary
This study follows people with idiopathic normal pressure hydrocephalus (iNPH) who are already scheduled for shunt surgery. Researchers measure changes in thinking skills and frailty one year after the procedure to identify which patients are most likely to improve. The goal is to better predict who will benefit from this surgical treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ventriculoperitoneal shunt
- What this could lead to
- If successful, this could help doctors predict which patients with normal pressure hydrocephalus will benefit most from shunt surgery, improving treatment decisions.
- What could go wrong
- This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all patients, and some may not improve after surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
276 people
The number who actually took part.
- Started
-
Sep 2018
- Finished
-
Jun 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
see inclusion criteria
- Ages
-
Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: • Diagnosed with iNPH and accepted for shunt surgery according to the American-European guidelines at Department of Neurosurgery, Oslo University Hospital, Rikshospitalet. Exclusion Criteria: * Non-native speakers of Norwegian * Patients who had completed ≤ 3 cognitive tests
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Geriatric Medicine, Oslo University Hospital
Oslo, Norway
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Other studies related to the condition(s) this trial covers.
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