Oslo University Hospital

This early-phase trial tests a cancer vaccine called Pseudovax, given with an immunotherapy drug (tislelizumab), in 10 adults with a rare abdominal cancer called pseudomyxoma peritonei that has a specific gene mutation (GNAS). The goal is to see if the combination is safe and can…

This study tests a Norwegian e-health program called DiaMester for adults with type 2 diabetes. The program aims to help participants lose weight and improve their diabetes control, with the goal of achieving remission. About 99 people will take part, and the study will measure w…

This study tests whether a higher dose of proton radiation can better control soft tissue sarcomas that cannot be surgically removed. About 40 adults in Norway will receive radiation over 4 weeks, with the highest dose focused on the tumor center. The main goal is to see if the t…

This study tests whether giving a shorter course of radiation (3 weeks instead of longer) before surgery for soft tissue sarcoma can reduce long-term side effects. Each patient's treatment is personalized by choosing between proton or standard X-ray radiation. The study will enro…

This study compares two types of weight-loss surgery in 220 adults with severe obesity. One surgery is a sleeve gastrectomy (stomach reduction), the other adds an intestinal bypass. Researchers will measure weight loss, acid reflux, and other health changes over time. Participant…

This study tests whether proton therapy, which targets tumors more precisely than standard photon radiation, is as effective for people with IDH-mutated grade 2 or 3 gliomas. About 225 adults aged 18-65 will be randomly assigned to receive either proton or photon therapy. The mai…

This study is for people with a type of liver cancer (intrahepatic cholangiocarcinoma) that cannot be removed by surgery. It compares two treatments delivered directly to the liver's blood supply—HAI-FUDR/DEX and SIRT—both given alongside standard chemotherapy. The goal is to shr…

This study compares two types of scans—CT and MRI—to see which one is better at determining if bladder cancer has spread into the muscle layer. About 150 adults with newly diagnosed bladder cancer will receive both scans before surgery, and the results will be checked against tis…

This study tests whether a remote expert can guide a bedside ultrasound to accurately detect fluid buildup in the belly after liver surgery. About 40 patients will be scanned within 72 hours of surgery. The goal is to see if this remote method works as well as a standard ultrasou…

This study tests whether combining spinal cord stimulation with a rehabilitation program can reduce long-term nerve pain in the legs and improve daily function. Ten adults aged 18-60 with nerve pain from back problems or injury will receive both treatments together. The goal is t…

This study tests a two-week intensive outpatient treatment for adults with PTSD. Up to 42 participants will receive daily therapy and be followed for 12 weeks. Researchers will measure changes in trauma symptoms and daily functioning using questionnaires and interviews.

This study compares two types of talk therapy for teenagers with eating disorders: family-based treatment and enhanced cognitive behavior therapy. The goal is to see if one works as well as the other in reducing eating disorder symptoms. About 200 teens who are medically stable a…

This study tests a new 5-day outpatient program called Temperament Based Therapy with Support (TBT-S) for adults with anorexia nervosa. Researchers want to see if adding TBT-S to standard care helps reduce eating disorder symptoms more than standard care alone. About 120 particip…

This study compares standard radiation therapy to a new 'dose-painting' method for people with head and neck cancer. The new approach gives higher radiation doses to the most active parts of the tumor while aiming to reduce severe side effects like mouth ulcers. About 100 partici…

This study compares two treatments for adults aged 20-65 with chronic low back pain lasting at least one year: lumbar fusion surgery or a multidisciplinary rehab program. The goal is to see which approach better reduces disability and improves daily life. Participants will be ran…

This study uses a special X-ray technique (RSA) to precisely measure bone growth in children who have had surgery to correct leg length differences or bowing. By tracking tiny markers, researchers hope to learn when it's best to remove temporary implants. The study involves 10 ch…

This study looks at how people with celiac disease react to gluten in liquid form (a shake) versus solid form (a cookie). Researchers want to see if one causes a stronger immune response. Thirty adults who follow a strict gluten-free diet will take part, giving blood samples and …

This study observes how doctors in Norway manage bile duct stones during gallbladder removal surgery. It compares two techniques—transcystic exploration and intraoperative ERCP—to see which works better and costs less. About 340 adults with small bile duct stones will take part, …

This study is for people who have had a spontaneous coronary artery dissection (SCAD), a rare heart condition that mostly affects women. Researchers will follow 300 participants for one year to learn about risk factors and complications. The study does not test any new treatments…

This study observes about 1,950 emergency patients with suspected sepsis to see how well certain blood markers (like calprotectin) and rapid DNA tests can detect infections. The goal is to improve diagnosis and tailor treatment to each patient. Participants are adults admitted to…

This pilot study tests a new instrument to help surgeons balance the knee's main ligament (MCL) during total knee replacement. The goal is to see if the tool makes the procedure more consistent and repeatable. About 40 adults with knee osteoarthritis who need a knee replacement w…

This pilot study aims to understand how adults with schizophrenia or related psychotic disorders experience a new type of talk therapy designed for self-disorders. Eight participants will receive the therapy and then be interviewed about their experience, including whether they f…