Oslo University Hospital

This study tested whether a procedure called extracorporeal photophoresis (ECP) — where a patient's blood is treated with light outside the body — could prevent graft-versus-host disease (GVHD) in 158 people receiving stem cell transplants for blood cancers. GVHD is a serious com…

This study looked at how well people aged 75 and older with stage III colon cancer handle chemotherapy after surgery. Researchers measured changes in daily living activities, side effects, and quality of life. The goal is to better identify which older patients can benefit from c…

This study tested whether a clot-dissolving medicine called tenecteplase can restore vision in people who suddenly lose sight due to a blocked artery in the eye. 81 adults with central retinal artery occlusion received either tenecteplase or a placebo within 4.5 hours of symptoms…

This study tested whether using EEG brain-wave monitoring during anesthesia helps doctors give the right amount of medicine, so patients wake up faster after surgery. About 100 adults having general anesthesia took part. Researchers also checked if this approach reduces short-ter…

This study looked at whether cancer patients already taking strong opioids (like morphine) still need paracetamol for pain relief. 204 adults with advanced cancer who were on both medications took part. Half stopped paracetamol and got a placebo instead, while the other half kept…

This study looked at 80 adults having wrist fracture surgery to see if using a lower concentration of the numbing drug ropivacaine (3.75 mg/ml vs. 7.5 mg/ml) could reduce the intense "rebound pain" that often happens when the nerve block wears off. Participants received one of th…

This study tested whether a single intravenous dose of iron can improve exercise capacity in people with severe aortic stenosis and iron deficiency who are scheduled for valve replacement. About 100 participants received either iron or a placebo. The main goal was to see if the i…

This study looked at whether cutting out certain carbs (FODMAPs) can reduce ongoing stomach issues in people with celiac disease who already follow a strict gluten-free diet. Researchers surveyed and then ran a controlled trial with 80 adults. The goal was to see if a low FODMAP …

This study examined tissue samples from 200 people having spine surgery to see if bacteria or genetic markers are linked to chronic low back pain and bone changes. Researchers collected samples from discs, bone, and skin, and used advanced DNA sequencing to detect bacteria. The g…

This study looked at how three common opioids (morphine, oxycodone, and fentanyl) affect feelings like anxiety, relaxation, and pain right before surgery. It also tracked how much opioid painkillers people used after surgery and what factors predicted long-term use or ongoing pai…

This study looked at how stable a new type of uncemented knee implant is in people with knee osteoarthritis. 31 patients received the implant and were followed for 2 years using special X-rays to measure any movement. The goal was to see if the implant stays firmly in place over …

This study involved 33 adults with celiac disease who ate small amounts of different gluten types to see how their immune systems reacted. The goal was to find better ways to test whether processed gluten in foods is safe for people with celiac disease. Participants completed fiv…

This study checked if the amount of propofol (an anesthesia drug) in children's breath matches the amount in their blood during eye surgery. 32 children having planned eye surgery took part. Researchers compared breath measurements with blood samples and brain activity monitors. …

This study looked at whether carbetocin, a drug used to prevent bleeding after childbirth, is less harmful to the heart than the standard drug oxytocin. Researchers measured heart damage markers in 240 healthy pregnant women after they received one of the two drugs. The goal was …

This study looked at how often stroke patients have vision problems, both right after the stroke and three months later. Researchers tested 127 patients' eyesight and compared results with brain scans. The goal was to better understand and detect these vision issues, not to test …

This study looked at how stable a new knee implant (GMK Sphere) is in people with knee osteoarthritis. Researchers used a special X-ray technique to measure any tiny movements of the implant over 5 years. The goal was to gather information that could help design better, longer-la…

This study tested a quick, one-minute checklist to identify women at high risk for severe pain after gynecologic day surgery. Researchers followed 487 women and checked if the tool could accurately predict who would have severe pain at home. The goal is to help doctors give bette…