700-Patient study aims to unravel the mystery of freezing gait
NCT ID NCT07386015
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is gathering information from 700 people with Parkinson's disease or similar conditions who experience freezing of gait—a sudden inability to move their feet while walking. Researchers will track symptoms, walking patterns, and falls over three years using questionnaires and routine tests. No new treatments are being tested; the goal is to better understand the condition and improve future care.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 700 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Nov 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population includes adults aged 30 to 85 years with freezing of gait or gait and balance impairment. Participants are diagnosed with Parkinson's disease or other parkinsonian or related neurological disorders associated with freezing of gait, including but not limited to parkinsonian syndromes and other causes of gait dysfunction. Both participants with established freezing of gait and participants at high risk for developing freezing of gait are included. All participants are recruited from neurology and related specialty clinics at participating centers and are followed longitudinally as part of a prospective observational patient registry.
- Ages
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30 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age 30-85 years 2. Presence of freezing of gait or non-freezing gait or balance impairment 3. Diagnosis of Parkinson's disease or related parkinsonian disorders according to established international criteria (including PD, PSP, MSA, DLB, CBD, vascular parkinsonism, or idiopathic normal pressure hydrocephalus) 4. Ability to complete gait and balance assessment tasks independently or with assistance 5. Ability and willingness to provide written informed consent Exclusion Criteria: 1. Severe dementia (Mini-Mental State Examination score \< 10) 2. Severe psychiatric disorders interfering with study participation 3. Severe cardiopulmonary, musculoskeletal, or other medical conditions significantly affecting gait safety 4. Stroke, fracture, or other major medical events within the past 3 months 5. Inability to comply with follow-up procedures 6. Refusal of video or speech data collection
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tianjin Huanhu Hospital
RECRUITINGTianjin, Tianjin Municipality, 300350, China
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