Could a new drug help Kids' immune systems fight brain tumors?
NCT ID NCT04049669
First seen Jan 11, 2026 · Last updated May 18, 2026 · Updated 17 times
Summary
This study tests a drug called indoximod, which aims to help the immune system fight brain tumors. It is for children aged 3 to 21 with certain types of progressive brain cancer or a newly diagnosed brainstem tumor (DIPG). Participants receive indoximod alongside standard chemotherapy and radiation. The goal is to see if adding this drug improves survival compared to standard treatment alone.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Augusta University, Georgia Cancer Center
Augusta, Georgia, 30912, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Emory University, Children's Heathcare of Atlanta
Druid Hills, Georgia, 30322, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
Explore the condition pages connected to this study.