New combo therapy aims to outsmart Kids' brain tumors
NCT ID NCT04049669
First seen Jan 11, 2026 · Last updated May 14, 2026 · Updated 16 times
Summary
This study tests whether adding the drug indoximod to standard chemotherapy and radiation can help children aged 3 to 21 with certain brain cancers. The drug aims to boost the body's immune system to fight tumors more effectively. The trial includes children with progressive glioblastoma, medulloblastoma, or ependymoma, as well as those newly diagnosed with a type of brainstem tumor called DIPG.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Augusta University, Georgia Cancer Center
Augusta, Georgia, 30912, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Emory University, Children's Heathcare of Atlanta
Druid Hills, Georgia, 30322, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
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