DIFFUSE INTRINSIC PONTINE GLIOMA
Clinical trials for DIFFUSE INTRINSIC PONTINE GLIOMA explained in plain language.
Never miss a new study
Get alerted when new DIFFUSE INTRINSIC PONTINE GLIOMA trials appear
Sign up with your email to follow new studies for DIFFUSE INTRINSIC PONTINE GLIOMA, keep track of the ones that matter, and come back to a personal dashboard instead of checking manually.
Genom att skicka in godkänner du våra Användarvillkor
-
Could a Virus-Fighting vaccine shrink deadly childhood brain tumors?
⭐️ VACCINE ⭐️ Recruiting nowThis study tests a vaccine called PEP-CMV in 120 children and young adults with aggressive brain tumors (high-grade glioma, DIPG, or recurrent medulloblastoma). The vaccine targets a protein from a common virus (CMV) that often hides in these tumors, aiming to train the immune sy…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE2 • Sponsor: Nationwide Children's Hospital • Aim: ⭐️ VACCINE ⭐️
Last updated May 22, 2026 13:54 UTC
-
Experimental vaccine plus immunotherapy offers new hope for children with deadly brain tumors
Disease control Recruiting nowThis early-stage trial tests a new vaccine (rHSC-DIPGVax) combined with two immunotherapy drugs (BALSTILIMAB and ZALIFRELIMAB) in children with DIPG or diffuse midline glioma. The vaccine is designed to help the immune system recognize and attack tumor cells. The main goal is to …
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE1 • Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Disease control
Last updated May 26, 2026 11:57 UTC
-
Hope for kids with DIPG: major trial tests promising drug
Disease control Recruiting nowThis phase 3 trial tests whether the drug ONC201 works better than everolimus for children with diffuse intrinsic pontine glioma (DIPG), a rare and aggressive brain tumor. About 433 participants will receive one of the two drugs, and can switch if their disease gets worse. The go…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE3 • Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Disease control
Last updated May 26, 2026 11:55 UTC
-
Sound waves may help chemo reach deadly childhood brain tumors
Disease control Recruiting nowThis early-stage study tests whether focused ultrasound can safely open the blood-brain barrier in children with progressive diffuse midline glioma (DMG), a rare and aggressive brain tumor. The goal is to allow more of the chemotherapy drug etoposide to reach the tumor while redu…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE1 • Sponsor: Columbia University • Aim: Disease control
Last updated May 26, 2026 11:54 UTC
-
Engineered t cells target deadly brain cancers in new trial
Disease control Recruiting nowThis study tests a new treatment for people with brain tumors that have a protein called GD2. The treatment uses the patient's own immune cells (T cells) that are modified in a lab to recognize and attack the tumor. A special gene is added to help these cells survive longer in th…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated May 26, 2026 11:50 UTC
-
Targeted brain tumor attack: new trial hopes to control childhood gliomas
Disease control Recruiting nowThis study tests whether giving two cancer drugs (cetuximab and bevacizumab) directly into the brain's blood vessels each month is safe and can shrink or control relapsed brain tumors in people under 22. About 20 participants with specific types of glioma will receive the treatme…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE1, PHASE2 • Sponsor: University of Miami • Aim: Disease control
Last updated May 26, 2026 11:46 UTC
-
New hope for kids with deadly brain tumors: adaptive trial tests drug combos
Disease control Recruiting nowThis study is for children and young adults with diffuse midline gliomas (DMGs), including DIPG, a rare and aggressive brain tumor. The trial tests whether combining the drug ONC201 with other new agents can help control the disease. About 360 participants will receive different …
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 26, 2026 11:08 UTC
-
New hope for deadly brain tumors: experimental combo targets DIPG
Disease control Recruiting nowThis study tests whether adding an experimental drug called VRT106 to standard radiation therapy can help control a rare, fast-growing brain tumor called diffuse midline glioma (including DIPG). About 10 adults aged 18 to 75 will receive the combination treatment. The main goal i…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE2 • Sponsor: Guangzhou Virotech Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated May 26, 2026 11:08 UTC
-
New hope for kids with aggressive brain tumors: targeted drug combo after radiation
Disease control Recruiting nowThis study tests whether adding two different drug combinations after radiation can help children and young adults with high-grade gliomas (including DIPG) live longer. One group receives ribociclib plus everolimus, and another receives ribociclib plus temozolomide, based on the …
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE2 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated May 26, 2026 10:35 UTC
-
New hope for kids with rare brain cancer: targeted drug shows promise
Disease control Recruiting nowThis study tests a drug called larotrectinib in children (up to age 21) with a newly diagnosed, aggressive brain tumor (high-grade glioma) that has a specific genetic change (NTRK fusion). The goal is to see if the drug can shrink or control the tumor after two cycles, and to che…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: EARLY_PHASE1 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
-
New drug cocktail aims to stall childhood cancers
Disease control Recruiting nowThis study tests a new oral drug, AMXT 1501, combined with another drug called DFMO for children and young adults (up to age 21) with certain cancers like neuroblastoma, brain tumors, and sarcomas. The first part finds the safest dose, and the second part checks if the combo help…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE1, PHASE2 • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
-
New hope for kids with rare brain cancer: targeted drug shows promise
Disease control Recruiting nowThis study tests a drug called lorlatinib in children (ages 1-21) with a newly diagnosed, aggressive brain tumor that has a specific genetic change (ALK or ROS1 fusion). The goal is to see if the drug can shrink or control the tumor and to check its safety when given alone or wit…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: EARLY_PHASE1 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
-
Engineered immune cells injected directly into the brain show promise for childhood cancers
Disease control Recruiting nowThis early-stage study is testing whether specially engineered immune cells (CAR T cells) can be safely given directly into the brain or spinal fluid of children and young adults with aggressive brain tumors like DIPG or recurrent medulloblastoma. The cells are designed to recogn…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
-
Worldwide effort to unlock secrets of rare childhood brain cancer
Knowledge-focused Recruiting nowThis study creates a central registry and tissue bank for people of any age diagnosed with DIPG or DMG, rare and aggressive brain tumors. Researchers will collect medical information, scans, and tumor samples to study the biology of these cancers. The goal is to help scientists w…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated May 26, 2026 11:45 UTC
-
Brain tumor DNA test could pave way for personalized treatment in kids
Knowledge-focused Recruiting nowThis study aims to analyze the genetic makeup of brain tumors in children, teens, and young adults (ages 1 to 39) newly diagnosed with high-grade glioma, including a type called DIPG. By identifying specific genetic changes in each tumor, researchers hope to match patients with m…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Sponsor: Nationwide Children's Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 10:35 UTC