Could a common antiviral protect babies from CMV in the womb?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria : * Age ≥ 18 years, * Fœtal Infection with CMV authenticated by the positivity of the research of the viral genome by PCR in the amniotic liquid, * Echographic Assessment revealing at least one cerebral extra anomaly being able to be in connection with the infection with CMV, * And/or one isolated cerebral anomaly : * Ventriculomégalie measured with the ventricular crossroads \< 15mm * Signs of lenticulo-striated vasculopathy * Intraparenchymateuses calcifications * Intra-ventricular adherences * And/or biological signs of generilazed infection to CMV : * fetal viremia \> 3000 copies/ml * platelet \< 100 000/cc * Absence of request for termination of pregnancy from the start, * Acceptance of a strict follow-up by a Multi-field Center of Prenatal diagnosis and of an optimal observance of the founded treatment, * Collection of the written assent to take part in the test. * Affiliation with a mode of social security or equivalent. Exclusion criteria : * Not affiliation with a mode of social security (profit or having right) * Patient of less than 18 years, * Patient presenting another pathology obstetrical or medical (in particular hepatic or renal) preexistent to tracking or contra-indicating the use of valacyclovir, * Patientes whose fœtus does not present any echographic sign being able to be in connection with the infection with CMV, * Patientes whose fœtus presents at least one cerebral echographic anomaly : Ventriculomégalie measured with the ventricular crossroads ≥ 15mm Hyperechogenicity periventriculaire Hydrocephaly Microcephaly Increase cuts large retro-cérébelleuse cistern Hypoplasy vermienne Porencephaly Lissencephaly Cysts périventriculaires Hypoplasy of the callous body * Patient under any other active antiviral treatment against CMV, * Patient taking part in another therapeutic test, * Patient refusing to sign the enlightened assent, * Patient formulating a request for medical interruption of pregnancy before inclusion.