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Engineered immune cells take on Hard-to-Treat cancers

NCT ID NCT04119024

First seen Nov 01, 2025 · Last updated Jun 14, 2026 · Updated 40 times

Summary

This early-phase trial tests a new treatment for people with advanced melanoma or other solid tumors that have spread. Doctors take a patient's own immune cells, modify them in a lab to better recognize and attack cancer, and give them back after a short course of chemotherapy. The main goals are to find a safe dose and see if the cells can shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

    Contact Email: •••••@•••••

    Contact

  • Stanford Cancer Institute

    RECRUITING

    Stanford, California, 93405, United States

    Contact

    Contact Email: •••••@•••••

  • UCLA / Jonsson Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Adenocarcinoma of Lung Adenoma, Islet Cell adrenal carcinoma breast neoplasm cancer cutaneous melanoma melanoma Neoplasm Metastasis neuroendocrine neoplasm paraganglioma pheochromocytoma Squamous Cell Carcinoma of Head and Neck Thyroid Neoplasms Uveal Melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.