New combo therapy aims to calm IBS diarrhea
NCT ID NCT06684470
First seen Jan 11, 2026 · Last updated Jun 16, 2026 · Updated 23 times
Summary
This early study at Mayo Clinic tests whether adding a medication called mirtazapine to a low-FODMAP diet works better than diet alone for easing IBS with diarrhea. About 20 adults aged 18-70 will take part. The goal is to reduce belly pain, bloating, and improve stool consistency.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mayo Clinic
RECRUITINGJacksonville, Florida, 32224, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.