New combo therapy aims to calm IBS diarrhea

NCT ID NCT06684470

First seen Jan 11, 2026 · Last updated Jun 16, 2026 · Updated 23 times

Summary

This early study at Mayo Clinic tests whether adding a medication called mirtazapine to a low-FODMAP diet works better than diet alone for easing IBS with diarrhea. About 20 adults aged 18-70 will take part. The goal is to reduce belly pain, bloating, and improve stool consistency.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic

    RECRUITING

    Jacksonville, Florida, 32224, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.