Hydration hype or help? new study tests water vs. diet drinks
NCT ID NCT07179107
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how different amounts of water and non-sugar drinks affect hydration, blood sugar, and heart health in 144 adults. Participants will follow specific drinking plans over several weeks. The goal is to see if simply drinking more fluids—with or without sweeteners—can lower the risk of diabetes and heart disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- water and non-sugar-sweetened beverages
- What this could lead to
- If successful, this could show that drinking more water or non-sugar beverages improves blood sugar control and heart health, offering a simple way to reduce disease risk.
- What could go wrong
- This is a small, early-stage study with only 144 participants, so results may not apply to everyone. It tests short-term effects, not long-term health outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 144 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * BMI 18.5-24.9 or 30.0-39.9 kg/m2 * HbA1c ≤7% * Age 20-65 y * available for 8 consecutive weeks same day and time Exclusion Criteria: * Diabetes * HbA1c \>7% BMI ≤18.5, BMI of 25 to \<30, or ≥ 40 kg/m2 * night shifting work * losing or gaining weight during the last 2 months (\>5 lbs. fluctuation) * thyroid medication * bariatric surgery * Habitual strenuous exercise (\>120 min/week) Strenuous exercise is defined as activities that take hard physical effort and make you breathe much harder than normal. * Construction and other workers that spend signifant portion of their work day outdoors * Commuting by bicycle * Eating disorders * Use of aspirin during the duration of the study * Cancer * Renal disease (including kidney stones or recurrent urinary track infections * Hepatic disease * Cardiac conditions * Current infection requiring medication * Chronic, contagious, infectious diseases such as tuberculosis, Hepatitis A, B, C, or HIV * Medication that could affect appetite or body weight regulation * GLP1-RA medication * Anti-depressent SSRI medication * Testosterone replacement therapy * Participating in another study at the same time * Unable to abstain from alcohol during the study * Unable to limit caffeinated beverage intake to 1 cup per day * Donated blood during the past two months * Uneasibly acessable veins * Does not have smart phone
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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850 PBC
RECRUITINGPhoenix, Arizona, 85004, United States
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850 Phoenix Bioscience Core
NOT_YET_RECRUITINGPhoenix, Arizona, 85004, United States
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