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New hybrid heart procedure tested for Tough-to-Treat AFib in heart failure patients

NCT ID NCT05411614

First seen Nov 18, 2025 · Last updated May 22, 2026 · Updated 22 times

Summary

This study tests if a two-step hybrid ablation procedure works better than standard catheter ablation for controlling heart rhythm in people with persistent atrial fibrillation (a type of irregular heartbeat) and heart failure. About 120 adults with enlarged left atria and reduced heart pumping function will be randomly assigned to one of the two procedures. The main goal is to see which approach better prevents long episodes of irregular heartbeat without needing rhythm-control medications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ashford & St Peters Hospital NHS Trust

    RECRUITING

    Chertsey, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cromwell Hospital

    ACTIVE_NOT_RECRUITING

    London, United Kingdom

  • Epsom General Hospital

    RECRUITING

    Epsom, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Surrey County Hospital

    RECRUITING

    London, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St Anthonys Hospital

    ACTIVE_NOT_RECRUITING

    London, United Kingdom

  • St Georges University of London

    RECRUITING

    London, United Kingdom

    Contact Email: •••••@•••••

  • St Georges at Kingston Hospital

    RECRUITING

    London, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.