Smart drugs take on rare salivary gland cancer in new trial
NCT ID NCT05408845
First seen Jun 25, 2026 · Last updated Aug 18, 2026 · Updated 3 times
Summary
This phase II trial is testing whether newer targeted drugs (trastuzumab emtansine and trastuzumab deruxtecan) work better than standard chemotherapy plus trastuzumab for people with HER2-positive or HER2-low salivary gland cancer that has come back, spread, or cannot be removed. About 146 participants will be enrolled. The goal is to see if these antibody-drug conjugates can slow tumor growth or shrink tumors more effectively.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Trastuzumab emtansine (T-DM1) and trastuzumab deruxtecan, along with docetaxel chemotherapy
- What this could lead to
- If successful, this trial could point toward more effective, targeted treatment options for people with HER2-positive or HER2-low salivary gland cancer that has spread or cannot be removed.
- What could go wrong
- This is a mid-stage (phase II) trial with 146 participants, so results are not definitive. The newer drugs may not work better than standard therapy, and side effects from the chemotherapy-linked antibodies can be serious.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
About 146 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Mar 2023
- Expected to finish
-
Jul 2032
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Pathologically (histologically or cytologically) proven diagnosis of HER2-positive OR HER2-low expressing recurrent/metastatic salivary gland cancer (SGC) * HER2-positive cohort: * Note: The majority of HER2-positive SGCs are salivary duct carcinoma (SDCs), but to a lesser extent, other SGC subtypes can be HER2-positive (e.g., adenocarcinomas, mucoepidermoid carcinomas, etc.) and are eligible to be included on the study. Additionally, pathologists may sign out SDCs under other descriptors (e.g., ex-pleomorphic adenoma, adenocarcinoma), and these would be eligible if they are HER2-positive. * Note: HER2 evaluation based on local site immunohistochemistry (IHC), fluorescent in-situ hybridization (FISH), or local/commercial next-generation sequencing (NGS) is required. Any one of the following criteria observed in a primary tumor or metastasis would meet the study definition for "HER2-positive": * Immunohistochemistry (IHC) (3+) per the College of American Pathologists (CAP) breast cancer guidelines * Gene amplification by FISH (HER2/CEP17 ratio \>= 2.0) * Gene amplification by NGS (fold change \>= 2) * HER2-low expressing cohort: * Note: Local HER2 evaluation by immunohistochemistry (IHC) or fluorescent in-situ hybridization (FISH) is required. Any one of the following criteria observed in a primary tumor or metastasis would meet the study definition for "HER2-low": * IHC 1+ per the College of American Pathologists (CAP) breast cancer guidelines * IHC 2+ without evidence of amplification by FISH * Patients with unresectable disease who are not candidates for curative surgery or radiation OR recurrent OR metastatic disease that is evident on radiologic imaging * Patients with treated brain metastases are eligible if follow-up brain imaging after central nervous system (CNS)-directed therapy shows no evidence of progression * Patients with new or progressive brain metastases (active brain metastases) or leptomeningeal disease are eligible if the treating physician determines that immediate CNS specific treatment is not required and is unlikely to be required during the first cycle of therapy * HER2-positive cohort: Measurable or non-measurable disease by the RECIST v1.1 criteria. HER2-low expressing cohort: Measurable disease by the RECIST v1.1 criteria * History/physical examination within 30 days prior to registration * The following imaging within 60 days prior to registration: * CT or MRI of the neck (diagnostic quality with contrast, unless contraindicated) AND * CT scan of the chest (diagnostic quality with contrast, unless contraindicated) AND * If clinically indicated, CT or MRI of the abdomen and pelvis (diagnostic quality with contrast, unless contraindicated) * Age \>= 18 * Left ventricular ejection fraction (LVEF) \>= 50% assessed by echocardiogram or multigated acquisition (MUGA) scan within 30 days prior to registration * Zubrod (Eastern Cooperative Oncology Group \[ECOG\]) Performance Status of 0-2 within 14 days prior to registration * Absolute neutrophil count (ANC) \>= 1,500 cells/mm\^3 (within 14 days prior to registration) * Platelets \>= 100,000 cells/mm\^3 (within 14 days prior to registration) * Hemoglobin \>= 9.0 g/dL (within 14 days prior to registration) * HER2-positive cohort: Note: The use of transfusion or other intervention to achieve hemoglobin \[Hgb\] \>= 9.0 g/dL is acceptable * HER2-low expressing cohort: Note: Transfusion (red blood cell or platelet) or granulocyte-colony stimulating factor (granulocyte colony-stimulating factor \[G-CSF\]) is not allowed * Serum creatinine =\< 1.5 x upper limit of normal (ULN) OR calculated creatinine clearance (CrCl) \>= 30 mL/min by the Cockcroft-Gault formula (within 14 days prior to registration) * HER2-positive cohort: Total bilirubin =\< 1.5 x ULN (within 14 days prior to registration) (Not applicable to patients with known Gilbert's syndrome) (within 14 days prior to registration) * HER2-positive cohort: Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =\< 1.5 x ULN (within 14 days prior to registration) * HER2-low expressing cohort: Total bilirubin ≤ 1.5 x ULN if no liver metastases; or \< 3 x ULN in the presence of documented Gilbert's Syndrome or liver metastases (within 14 days prior to registration) (within 14 days prior to registration) * HER2-low expressing cohort: AST and ALT ≤ 3 x ULN if no liver metastases; or \< 5 x ULN with liver metastases (within 14 days prior to registration) * HER2-low expressing cohort: Serum albumin ≥ 2.5 g/dL (within 14 days prior to registration) * Known human immunodeficiency virus (HIV) infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months prior to registration are eligible for this trial. Testing is not required for entry into protocol * For patients with known evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated * Note: Known positive test for hepatitis B virus surface antigen (HBV sAg) indicating acute or chronic infection would make the patient ineligible unless the viral load becomes undetectable on suppressive therapy. Patients who are immune to hepatitis B (anti-hepatitis B surface antibody positive) are eligible (e.g., patients immunized against hepatitis B) * For patients with a known history of hepatitis C virus (HCV) infection, they must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load * Note: Known positive test for hepatitis C virus ribonucleic acid (HCV RNA) indicating acute or chronic infection would make the patient ineligible unless the viral load becomes undetectable on suppressive therapy * Negative urine or serum pregnancy test (in persons of childbearing potential) within 14 days prior to registration. Childbearing potential is defined as any person who has experienced menarche and who has not undergone surgical sterilization (hysterectomy or bilateral oophorectomy) or who is not postmenopausal * Willing to use highly effective contraceptives for participants of childbearing potential (participants who may become pregnant or who may impregnate a partner) during therapy and for 7 months following last dose of study drug; this inclusion is necessary because the treatment in this study may be significantly teratogenic. Women must refrain from donating eggs during this same period * Men with partners of childbearing potential must be willing to use a highly effective form of non-hormonal contraception or two effective forms of non-hormonal contraception by the patient and/or partner, and to continue the use of contraception for the duration of study treatment and for at least 7 months after the last dose of study treatment. Male patients whose partners are pregnant should use condoms for the duration of the pregnancy. Men must refrain from donating sperm during this same period * Prior to registration, patients who have had chemotherapy or palliative-intent radiotherapy must have all toxicities related to prior treatment recovered to ≤ grade 1 * Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial * The patient or a legally authorized representative must provide study-specific informed consent prior to study entry and, for patients treated in the United States (U.S.), authorization permitting release of personal health information Exclusion Criteria: * HER2-positive cohort: Prior systemic therapy for the study cancer in the unresectable or recurrent and/or metastatic disease setting * Note: Prior chemotherapy for a different cancer is allowed; prior androgen receptor targeted therapy in any setting is allowed; prior systemic therapy, including HER2-directed therapies given as neoadjuvant therapy, adjuvant therapy, and/or concurrently with radiation is allowed * HER2-low expressing cohort: HER2 directed therapy for unresectable or recurrent or metastatic disease is not allowed * Severe, active co-morbidity defined as follows: * Unstable angina requiring hospitalization in the last 6 months * Myocardial infarction within the last 6 months * New York Heart Association Functional Classification III/IV (Note: Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification.) * Persistent grade 3-4 (CTCAE version 5.0) electrolyte abnormalities that cannot be reversed despite replacement as indicated by repeat testing * Patient must not have an active infection requiring IV antibiotics, antivirals, or antifungals * HER2-positive cohort only: \>= grade 3 peripheral neuropathy * Interstitial lung disease or pulmonary fibrosis, organizing pneumonia (e.g., bronchiolitis obliterans), drug-induced pneumonitis, or idiopathic pneumonitis, or evidence of active pneumonitis on chest CT scan * Any hemorrhage or bleeding event grade \>= 3 within 28 days prior to registration * History of allergic reactions to compounds of similar chemical or biologic composition to: HER2-positive cohort: ado-trastuzumab emtansine, trastuzumab, and/or docetaxel (or any of their excipients). HER2-low expressing cohort: DS-8201a (trastuzumab deruxtecan), trastuzumab * History of exposure to the following cumulative doses of anthracyclines: * Doxorubicin or liposomal doxorubicin \> 500 mg/m\^2 * Epirubicin \> 900 mg/m\^2 * Mitoxantrone \> 120 mg/m\^2 * Note: If another anthracycline, or more than one anthracycline has been used, the cumulative dose must not exceed the equivalent of doxorubicin 500 mg/m\^2 * HER2-low expressing cohort only: Receipt of live, attenuated vaccine (messenger ribonucleic acid \[mRNA and replication deficient adenoviral vaccines are not considered attenuated live vaccines) within 30 days prior to the first dose of DS-8201a (trastuzumab deruxtecan) * Pregnancy and individuals unwilling to discontinue nursing
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Metastatic salivary gland carcinoma are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The study's own enquiry address
This study publishes an address for enquiries. See it below .
-
The places running it
144 sites. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
-
Abbott-Northwestern Hospital
RECRUITINGMinneapolis, Minnesota, 55407, United States
-
Arnold Palmer Cancer Center Medical Oncology Norwin
RECRUITINGN. Huntingdon, Pennsylvania, 15642, United States
Contact Email: •••••@•••••
-
Boston Medical Center
RECRUITINGBoston, Massachusetts, 02118, United States
-
Broadlawns Medical Center
RECRUITINGDes Moines, Iowa, 50314, United States
-
Cancer Centers of Southwest Oklahoma Research
RECRUITINGLawton, Oklahoma, 73505, United States
-
Carle Cancer Center
RECRUITINGUrbana, Illinois, 61801, United States
Contact Email: •••••@•••••
-
Carle Physician Group-Effingham
RECRUITINGEffingham, Illinois, 62401, United States
Contact Email: •••••@•••••
-
Carle Physician Group-Mattoon/Charleston
RECRUITINGMattoon, Illinois, 61938, United States
Contact Email: •••••@•••••
-
Carle at The Riverfront
RECRUITINGDanville, Illinois, 61832, United States
Contact Email: •••••@•••••
-
Carlisle Regional Cancer Center
RECRUITINGCarlisle, Pennsylvania, 17015, United States
-
City of Hope Comprehensive Cancer Center
ACTIVE_NOT_RECRUITINGDuarte, California, 91010, United States
-
City of Hope at Irvine Lennar
ACTIVE_NOT_RECRUITINGIrvine, California, 92618, United States
-
Dartmouth Cancer Center - North
SUSPENDEDSaint Johnsbury, Vermont, 05819, United States
-
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
RECRUITINGLebanon, New Hampshire, 03756, United States
-
Divine Providence Hospital
RECRUITINGWilliamsport, Pennsylvania, 17754, United States
-
Emory University Hospital Midtown
RECRUITINGAtlanta, Georgia, 30308, United States
-
Fairview Southdale Hospital
RECRUITINGEdina, Minnesota, 55435, United States
-
Fred Hutchinson Cancer Center
RECRUITINGSeattle, Washington, 98109, United States
-
HaysMed
RECRUITINGHays, Kansas, 67601, United States
-
Hennepin County Medical Center
RECRUITINGMinneapolis, Minnesota, 55415, United States
-
Huntsman Cancer Institute/University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
Contact Email: •••••@•••••
-
IRMC Cancer Center
RECRUITINGIndiana, Pennsylvania, 15701, United States
-
Iowa Methodist Medical Center
RECRUITINGDes Moines, Iowa, 50309, United States
-
Kaiser Permanente Downtown Commons
RECRUITINGSacramento, California, 95814, United States
-
Kaiser Permanente Dublin
RECRUITINGDublin, California, 94568, United States
-
Kaiser Permanente Fresno Orchard Plaza
RECRUITINGFresno, California, 93720, United States
-
Kaiser Permanente Medical Center - Santa Clara
RECRUITINGSanta Clara, California, 95051, United States
-
Kaiser Permanente Moanalua Medical Center
RECRUITINGHonolulu, Hawaii, 96819, United States
-
Kaiser Permanente San Leandro
RECRUITINGSan Leandro, California, 94577, United States
-
Kaiser Permanente- Modesto MOB II
RECRUITINGModesto, California, 95356, United States
-
Kaiser Permanente-Fremont
RECRUITINGFremont, California, 94538, United States
-
Kaiser Permanente-Fresno
RECRUITINGFresno, California, 93720, United States
-
Kaiser Permanente-Modesto
RECRUITINGModesto, California, 95356, United States
-
Kaiser Permanente-Oakland
RECRUITINGOakland, California, 94611, United States
-
Kaiser Permanente-Roseville
RECRUITINGRoseville, California, 95661, United States
-
Kaiser Permanente-San Francisco
RECRUITINGSan Francisco, California, 94115, United States
-
Kaiser Permanente-Santa Rosa
RECRUITINGSanta Rosa, California, 95403, United States
-
Kaiser Permanente-Santa Teresa-San Jose
RECRUITINGSan Jose, California, 95119, United States
-
Kaiser Permanente-South Sacramento
RECRUITINGSacramento, California, 95823, United States
-
Kaiser Permanente-South San Francisco
RECRUITINGSouth San Francisco, California, 94080, United States
-
Kaiser Permanente-Vallejo
RECRUITINGVallejo, California, 94589, United States
-
Kaiser Permanente-Walnut Creek
RECRUITINGWalnut Creek, California, 94596, United States
-
Kaiser San Rafael-Gallinas
RECRUITINGSan Rafael, California, 94903, United States
-
Lawrence Memorial Hospital
RECRUITINGLawrence, Kansas, 66044, United States
-
Marshfield Medical Center - Minocqua
RECRUITINGMinocqua, Wisconsin, 54548, United States
Contact Email: •••••@•••••
-
Marshfield Medical Center - Weston
RECRUITINGWeston, Wisconsin, 54476, United States
Contact Email: •••••@•••••
-
Marshfield Medical Center-EC Cancer Center
RECRUITINGEau Claire, Wisconsin, 54701, United States
Contact Email: •••••@•••••
-
Marshfield Medical Center-Marshfield
RECRUITINGMarshfield, Wisconsin, 54449, United States
Contact Email: •••••@•••••
-
Marshfield Medical Center-Rice Lake
RECRUITINGRice Lake, Wisconsin, 54868, United States
Contact Email: •••••@•••••
-
Marshfield Medical Center-River Region at Stevens Point
RECRUITINGStevens Point, Wisconsin, 54482, United States
Contact Email: •••••@•••••
-
Mayo Clinic in Rochester
RECRUITINGRochester, Minnesota, 55905, United States
-
McFarland Clinic - Ames
ACTIVE_NOT_RECRUITINGAmes, Iowa, 50010, United States
-
Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
-
Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
-
Memorial Hospital East
RECRUITINGShiloh, Illinois, 62269, United States
-
Memorial Sloan Kettering Basking Ridge
RECRUITINGBasking Ridge, New Jersey, 07920, United States
-
Memorial Sloan Kettering Bergen
RECRUITINGMontvale, New Jersey, 07645, United States
-
Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
-
Memorial Sloan Kettering Commack
RECRUITINGCommack, New York, 11725, United States
-
Memorial Sloan Kettering Monmouth
RECRUITINGMiddletown, New Jersey, 07748, United States
-
Memorial Sloan Kettering Nassau
RECRUITINGUniondale, New York, 11553, United States
-
Memorial Sloan Kettering Westchester
RECRUITINGHarrison, New York, 10604, United States
-
Mercy Hospital
RECRUITINGCoon Rapids, Minnesota, 55433, United States
-
Mercy Medical Center - Des Moines
RECRUITINGDes Moines, Iowa, 50314, United States
-
Miami Cancer Institute
RECRUITINGMiami, Florida, 33176, United States
-
Mount Sinai Chelsea
ACTIVE_NOT_RECRUITINGNew York, New York, 10011, United States
-
Mount Sinai Hospital
RECRUITINGNew York, New York, 10029, United States
-
Ohio State University Comprehensive Cancer Center
RECRUITINGColumbus, Ohio, 43210, United States
-
Park Nicollet Clinic - Saint Louis Park
RECRUITINGSaint Louis Park, Minnesota, 55416, United States
-
ProHealth D N Greenwald Center
RECRUITINGMukwonago, Wisconsin, 53149, United States
-
ProHealth Oconomowoc Memorial Hospital
RECRUITINGOconomowoc, Wisconsin, 53066, United States
-
Regions Hospital
RECRUITINGSaint Paul, Minnesota, 55101, United States
-
Saint Anthony Regional Hospital
RECRUITINGCarroll, Iowa, 51401, United States
-
Saint Luke's Cancer Institute - Boise
RECRUITINGBoise, Idaho, 83712, United States
-
Saint Luke's Cancer Institute - Fruitland
RECRUITINGFruitland, Idaho, 83619, United States
-
Saint Luke's Cancer Institute - Meridian
RECRUITINGMeridian, Idaho, 83642, United States
-
Saint Luke's Cancer Institute - Nampa
RECRUITINGNampa, Idaho, 83687, United States
-
Saint Luke's Cancer Institute - Twin Falls
RECRUITINGTwin Falls, Idaho, 83301, United States
-
Salina Regional Health Center
RECRUITINGSalina, Kansas, 67401, United States
-
Sanford Bismarck Medical Center
RECRUITINGBismarck, North Dakota, 58501, United States
Contact Email: •••••@•••••
-
Sanford Broadway Medical Center
RECRUITINGFargo, North Dakota, 58122, United States
Contact Email: •••••@•••••
-
Sanford Cancer Center Oncology Clinic
RECRUITINGSioux Falls, South Dakota, 57104, United States
Contact Email: •••••@•••••
-
Sanford Joe Lueken Cancer Center
RECRUITINGBemidji, Minnesota, 56601, United States
Contact Email: •••••@•••••
-
Sanford Roger Maris Cancer Center
RECRUITINGFargo, North Dakota, 58122, United States
Contact Email: •••••@•••••
-
Sanford USD Medical Center - Sioux Falls
RECRUITINGSioux Falls, South Dakota, 57117-5134, United States
Contact Email: •••••@•••••
-
Siteman Cancer Center at Christian Hospital
RECRUITINGSt Louis, Missouri, 63136, United States
Contact Email: •••••@•••••
-
Siteman Cancer Center at Saint Peters Hospital
RECRUITINGCity of Saint Peters, Missouri, 63376, United States
Contact Email: •••••@•••••
-
Siteman Cancer Center at West County Hospital
RECRUITINGCreve Coeur, Missouri, 63141, United States
Contact Email: •••••@•••••
-
Siteman Cancer Center-South County
RECRUITINGSt Louis, Missouri, 63129, United States
Contact Email: •••••@•••••
-
Stanford Cancer Institute Palo Alto
RECRUITINGPalo Alto, California, 94304, United States
-
Swedish Cancer Institute-Issaquah
RECRUITINGIssaquah, Washington, 98029, United States
-
The Iowa Clinic PC
RECRUITINGWest Des Moines, Iowa, 50266, United States
-
The University of Kansas Cancer Center - Olathe
RECRUITINGOlathe, Kansas, 66061, United States
Contact Email: •••••@•••••
-
Trinity's Tony Teramana Cancer Center
RECRUITINGSteubenville, Ohio, 43952, United States
-
UCHealth Highlands Ranch Hospital
RECRUITINGHighlands Ranch, Colorado, 80129, United States
-
UCHealth University of Colorado Hospital
RECRUITINGAurora, Colorado, 80045, United States
-
UCSF Medical Center-Mission Bay
SUSPENDEDSan Francisco, California, 94158, United States
-
UI Health Care Mission Cancer and Blood - Ankeny Clinic
RECRUITINGAnkeny, Iowa, 50023, United States
-
UI Health Care Mission Cancer and Blood - Des Moines Clinic
RECRUITINGDes Moines, Iowa, 50309, United States
-
UI Health Care Mission Cancer and Blood - Laurel Clinic
RECRUITINGDes Moines, Iowa, 50314, United States
-
UI Health Care Mission Cancer and Blood - Waukee Clinic
RECRUITINGWaukee, Iowa, 50263, United States
-
UI Health Care Mission Cancer and Blood - West Des Moines Clinic
RECRUITINGClive, Iowa, 50325, United States
-
UI Healthcare Mission Cancer and Blood - Fort Dodge
RECRUITINGFort Dodge, Iowa, 50501, United States
Contact Email: •••••@•••••
-
UPMC Altoona
RECRUITINGAltoona, Pennsylvania, 16601, United States
-
UPMC Camp Hill
ACTIVE_NOT_RECRUITINGCamp Hill, Pennsylvania, 17011, United States
-
UPMC Cancer Center at UPMC Horizon
RECRUITINGFarrell, Pennsylvania, 16121, United States
-
UPMC Cancer Center at UPMC McKeesport
RECRUITINGMcKeesport, Pennsylvania, 15132, United States
-
UPMC Cancer Center at UPMC Northwest
RECRUITINGSeneca, Pennsylvania, 16346, United States
-
UPMC Cancer Center-Natrona Heights
RECRUITINGNatrona Heights, Pennsylvania, 15065, United States
-
UPMC Cancer Center-Uniontown
RECRUITINGUniontown, Pennsylvania, 15401, United States
-
UPMC Cancer Center-Washington
RECRUITINGWashington, Pennsylvania, 15301, United States
-
UPMC Cancer Centers - Arnold Palmer Pavilion
RECRUITINGGreensburg, Pennsylvania, 15601, United States
-
UPMC Hillman Cancer Center - Monroeville
RECRUITINGMonroeville, Pennsylvania, 15146, United States
Contact Email: •••••@•••••
-
UPMC Hillman Cancer Center - New Castle
RECRUITINGNew Castle, Pennsylvania, 16105, United States
-
UPMC Hillman Cancer Center - Part of Frick Hospital
RECRUITINGMount Pleasant, Pennsylvania, 15666, United States
-
UPMC Hillman Cancer Center - Passavant - Cranberry
RECRUITINGCranberry Township, Pennsylvania, 16066, United States
-
UPMC Hillman Cancer Center Erie
RECRUITINGErie, Pennsylvania, 16505, United States
Contact Email: •••••@•••••
-
UPMC Hillman Cancer Center at Butler Health System
RECRUITINGButler, Pennsylvania, 16001, United States
-
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
RECRUITINGMechanicsburg, Pennsylvania, 17050, United States
-
UPMC Hillman Cancer Center in Coraopolis
RECRUITINGMoon Township, Pennsylvania, 15108, United States
-
UPMC Memorial
RECRUITINGYork, Pennsylvania, 17408, United States
-
UPMC Pinnacle Cancer Center/Community Osteopathic Campus
RECRUITINGHarrisburg, Pennsylvania, 17109, United States
-
UPMC Western Maryland
RECRUITINGCumberland, Maryland, 21502, United States
-
UPMC-Heritage Valley Health System Beaver
RECRUITINGBeaver, Pennsylvania, 15009, United States
-
UPMC-Johnstown/John P. Murtha Regional Cancer Center
RECRUITINGJohnstown, Pennsylvania, 15901, United States
-
UPMC-Mercy Hospital
RECRUITINGPittsburgh, Pennsylvania, 15219, United States
-
UPMC-Passavant Hospital
RECRUITINGPittsburgh, Pennsylvania, 15237, United States
-
UPMC-Saint Clair Hospital Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15243, United States
-
UPMC-Saint Margaret
RECRUITINGPittsburgh, Pennsylvania, 15215, United States
-
UW Cancer Center at ProHealth Care
RECRUITINGWaukesha, Wisconsin, 53188, United States
-
United Hospital
RECRUITINGSaint Paul, Minnesota, 55102, United States
-
University Health Truman Medical Center
RECRUITINGKansas City, Missouri, 64108, United States
-
University of Alabama at Birmingham Cancer Center
ACTIVE_NOT_RECRUITINGBirmingham, Alabama, 35233, United States
-
University of Cincinnati Cancer Center-UC Medical Center
RECRUITINGCincinnati, Ohio, 45219, United States
Contact Email: •••••@•••••
-
University of Cincinnati Cancer Center-West Chester
RECRUITINGWest Chester, Ohio, 45069, United States
Contact Email: •••••@•••••
-
University of Kansas Cancer Center
RECRUITINGKansas City, Kansas, 66160, United States
-
University of Kansas Cancer Center - Lee's Summit
RECRUITINGLee's Summit, Missouri, 64064, United States
-
University of Kansas Cancer Center - North
RECRUITINGKansas City, Missouri, 64154, United States
-
University of Kansas Cancer Center-Overland Park
RECRUITINGOverland Park, Kansas, 66210, United States
-
University of Kansas Health System Saint Francis Campus
RECRUITINGTopeka, Kansas, 66606, United States
-
University of Kansas Hospital-Indian Creek Campus
RECRUITINGOverland Park, Kansas, 66211, United States
-
University of Kansas Hospital-Westwood Cancer Center
RECRUITINGWestwood, Kansas, 66205, United States
-
University of Kentucky/Markey Cancer Center
RECRUITINGLexington, Kentucky, 40536, United States
-
University of Michigan Rogel Cancer Center
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Email: •••••@•••••
-
University of New Mexico Cancer Center
RECRUITINGAlbuquerque, New Mexico, 87106, United States
-
University of Oklahoma Health Sciences Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
-
University of Pittsburgh Cancer Institute (UPCI)
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
-
VCU Massey Comprehensive Cancer Center
RECRUITINGRichmond, Virginia, 23298, United States
-
Vanderbilt University/Ingram Cancer Center
RECRUITINGNashville, Tennessee, 37232, United States
-
Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Email: •••••@•••••
-
Wayne State University/Karmanos Cancer Institute
ACTIVE_NOT_RECRUITINGDetroit, Michigan, 48201, United States
-
Weisberg Cancer Treatment Center
ACTIVE_NOT_RECRUITINGFarmington Hills, Michigan, 48334, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Three-Pronged attack shrink Hard-to-Treat head and neck cancers?
- New drug combo shows promise for rare salivary gland cancer
- Experimental combo targets Hard-to-Treat HER2 cancers
- New combo therapy aims to extend life in advanced head and neck cancer
- Hormone cocktail shows promise for rare salivary cancer
- Could a cancer pill before surgery help head and neck patients?